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- W1762630955 abstract "Endoscopic findings are essential in evaluating the disease activity in ulcerative colitis. The aim of this study was to evaluate how endoscopists assess individual endoscopic features of mucosal inflammation in ulcerative colitis, the inter-observer agreement, and the importance of the observers' experience. Five video clips of ulcerative colitis were shown to a group of experienced and a group of inexperienced endoscopists. Both groups were asked to assess eight endoscopic features and the overall mucosal inflammation on a visual analogue scale. The following statistical analyses were used; Contingency tables analysis, kappa analysis, analysis of variance, Pearson linear correlation analysis, general linear models, and agreement analysis. All tests were carried out two-tailed, with a significance level of 5%. The inter-observer agreement ranged from very good to moderate in the experienced group and from very good to fair in the inexperienced group. There was a significantly better inter-observer agreement in the experienced group in the rating of 6 out of 9 features (p < 0.05). The experienced and inexperienced endoscopists scored the ulcerations significantly different. (p = 0.05). The inter-observer variation of the mean score of erosions, ulcerations and endoscopic activity index in mild disease, and the scoring of erythema and oedema in moderate-severe disease was significantly higher in the inexperienced group. A correlation was seen between all the observed endoscopic features in both groups of endoscopists. Among experienced endoscopists, a set of four endoscopic variables (Vascular pattern, Erosions, Ulcerations and Friability) explained 92% of the variation in EAI. By including Granularity in these set 91% of the variation in EAI was explained in the group of inexperienced endoscopists. The inter-observer agreement in the rating of endoscopic features characterising ulcerative colitis is satisfactory in both groups of endoscopists but significantly higher in the experienced group. The difference in the mean score between the two groups is only significant for ulcerations. The endoscopic variables Vascular pattern, Erosions, Ulcerations and Friability explained the overall endoscopic activity index. Even though the present result is quite satisfactory, there is a potential of improvement. Improved grading systems might contribute to improve the consistency of endoscopic descriptions." @default.
- W1762630955 created "2016-06-24" @default.
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- W1762630955 date "2004-05-18" @default.
- W1762630955 modified "2023-10-10" @default.
- W1762630955 title "Inter-observer agreement in the assessment of endoscopic findings in ulcerative colitis" @default.
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- W1762630955 doi "https://doi.org/10.1186/1471-230x-4-9" @default.
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