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- W1763286001 abstract "The mechanism allowing a protein to search of a target sequence on DNA is currently described as an intermittent process composed of 3D diffusion in bulk and 1D diffusion along the DNA molecule. Due to the relevant charge of protein and DNA, electrostatic interaction should play a crucial role during this search. In this paper, we explicitly derive the mean field theory allowing for a description of the protein-DNA electrostatics in solution. This approach leads to a unified model of the search process, where 1D and 3D diffusion appear as a natural consequence of the diffusion on an extended interaction energy profile." @default.
- W1763286001 created "2016-06-24" @default.
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- W1763286001 date "2013-11-27" @default.
- W1763286001 modified "2023-09-27" @default.
- W1763286001 title "On the ion-mediated interaction between protein and DNA" @default.
- W1763286001 cites W379390718 @default.
- W1763286001 hasPublicationYear "2013" @default.
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