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- W1765005655 abstract "The aim of our study is:(1)to evaluate the prevalence of Pulmonary Hypertension (PH) in Idiopathic pulmonary fibrosis (IPF) patients (pts);(2)to determine the accuracy of PAPs measurement with Doppler echocardiography (DE) versus Right Heart Catheterization (RHC);(3)to analyze survival in pts with or without PH;(4)to determine any correlation between functional data and haemodynamic parameters. We analyzed 54 IPF pts referred to our Centre who underwent RHC. PH was defined when PAPm ≥25 mmHg. PH was diagnosed in 30/54 pts (55%, PAPm=30 ±5mmHg, PAPs=48±10, PW=11±3, RVP=3,1±2). There was a significant correlation between PAPs evaluated at DE and RHC (p 12 m: group B] and we observed a significant difference in survival between group A and B (p=0,0042, 35m versus 56), between group A and all other pts(group 2+B; p=0,0095, 35 versus 52).11(91%) of group A needed oxygen-therapy after a median time of 8m since IPF diagnosis, while 32(76%) of all other pts (group 2+B) after 16m(p=0.029). We observed a significant correlation between Six Min Walking test distance (WTD) performed in room air and PAPs at RHC(p=0.039). Our data confirms that PH has an high prevalence in IPF and RHC is the gold standard for PH diagnosis. An early onset of PH is related to a worst prognosis and to a precocious oxygen-therapy request. A decrease of WTD could help clinicians to suspect PH in IPF pts." @default.
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- W1765005655 date "2012-09-01" @default.
- W1765005655 modified "2023-09-28" @default.
- W1765005655 title "Precocious detection of pulmonary hypertension in idiopathic pulmonary fibrosis" @default.
- W1765005655 hasPublicationYear "2012" @default.
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