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- W176976024 abstract "背景与目的：研究N-烟酰基-L-天门冬氨酸遗传毒性,为临床安全用药提供理论依据。材料与方法：采用Ames试验、中国仓鼠卵巢细胞（CHO细胞）染色体畸变试验及小鼠微核试验对N-烟酰基-L-天门冬氨酸进行致突变性研究。结果：Ames试验中加S9与不加S9混合液的各剂量组回变菌落数与阴性对照无明显差别,且无剂量-效应关系。小鼠骨髓细胞微核率及CHO细胞染色体畸变率与阴性对照组比较,差别也无统计学意义（P〉0.05）。结论：在本实验条件下,N-烟酰基-L-天门冬氨酸无致突变作用。" @default.
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- W176976024 date "2007-01-01" @default.
- W176976024 modified "2023-09-24" @default.
- W176976024 title "N-烟酰基-L-天门冬氨酸的致突变性检测" @default.
- W176976024 hasPublicationYear "2007" @default.
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