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- W177092641 abstract "Autoimmune hepatitis (AIH) in childhood is an inflammatory liver disease characterized histologically by a dense portal tract mononuclear cell infiltrate and serologically by the presence of non-organ- and liver-specific autoantibodies and increased levels of IgG, in the absence of a known etiology. AIH usually responds to immunosuppressive treatment, which should be instituted as soon as a diagnosis is made. In pediatrics, as well as in young adults, AIH often presents acutely and has a more aggressive course than in older patients. In children there are two liver disorders in which the liver damage is likely to arise from an autoimmune attack: classical AIH and AIH/sclerosing cholangitis overlap syndrome (ASC). A possible autoimmune pathogenesis has also been postulated for the so-called post liver transplant de novo AIH, a condition originally described in children and later confirmed in adults." @default.
- W177092641 created "2016-06-24" @default.
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- W177092641 date "2008-01-23" @default.
- W177092641 modified "2023-10-18" @default.
- W177092641 title "Unique Aspects of Autoimmune Hepatitis in Children" @default.
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- W177092641 doi "https://doi.org/10.1007/978-1-59745-518-3_22" @default.
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