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- W1771031878 abstract "Anemia is common in cancer, and lymphoproliferative disease is no exception. Erythropoiesis-stimulating agents (ESA) have been used for renal anemia since 1986, and considerably later in cancer anemia. The first studies were published around 1993, but the use of ESA did not become common in cancer anemia until in the late 1990s. Cancer anemia is still under-treated. This review gives an overview of the use of ESA in hematologic malignancies. A background is given about this treatment in the cancer field generally. The pathophysiology of cancer anemia is described with special emphasis on the disturbances in iron metabolism. Functional iron deficiency has been shown to be both frequent and important as a hindrance for response to ESA treatment, and recent studies are reported in some detail, where the use of intravenous iron was shown to improve the response rate of ESA treatment." @default.
- W1771031878 created "2016-06-24" @default.
- W1771031878 creator A5012374853 @default.
- W1771031878 date "2008-04-01" @default.
- W1771031878 modified "2023-09-30" @default.
- W1771031878 title "Managing anemia in lymphoma and multiple myeloma" @default.
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- W1771031878 doi "https://doi.org/10.2147/tcrm.s1351" @default.
- W1771031878 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2504072" @default.
- W1771031878 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18728848" @default.
- W1771031878 hasPublicationYear "2008" @default.
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