Matches in SemOpenAlex for { <https://semopenalex.org/work/W1773280100> ?p ?o ?g. }
- W1773280100 endingPage "5" @default.
- W1773280100 startingPage "144" @default.
- W1773280100 abstract "Allogeneic red blood cell (RBC) transfusion is associated with significant increases in mortality and major morbidity in patients admitted to the intensive care unit, and the blood supplies it requires are an increasingly scarce and costly resource. Despite high levels of compliance with recommended transfusion thresholds in the ICU, RBC transfusion remains common. Novel interventions to reduce the incidence of RBC transfusion are required.To describe the study protocol for a randomised controlled trial, the Intravenous Iron or Placebo for Anaemia in Intensive Care (IRONMAN) trial, comparing intravenous (IV) iron with placebo in patients who are admitted to an ICU and are anaemic.A Phase IIb multicentre, randomised, placebo-controlled trial. Patients admitted to the ICU with a haemoglobin (Hb) level < 100 g/L and predicted to require critical care beyond the next calendar day will be randomly assigned in a 1 : 1 ratio to receive IV ferric carboxymaltose (500 mg) or placebo.The primary end point will be the mean number of RBC units transfused from study enrolment to discharge from hospital. Secondary end points will include change in Hb level and incidence of nosocomial infection.The IRONMAN trial is designed to determine whether IV iron administered to patients admitted to an ICU and who are anaemic is associated with a reduction in RBC transfusion, compared with placebo in addition to standard care. The results of this trial may determine whether a Phase III trial of IV iron in ICUs is feasible.Australian New Zealand Clinical Trials Registry (ACTRN12612001249842)." @default.
- W1773280100 created "2016-06-24" @default.
- W1773280100 creator A5007382269 @default.
- W1773280100 creator A5010197979 @default.
- W1773280100 creator A5013463984 @default.
- W1773280100 creator A5016898005 @default.
- W1773280100 creator A5032363710 @default.
- W1773280100 creator A5032701736 @default.
- W1773280100 creator A5034639222 @default.
- W1773280100 creator A5040469659 @default.
- W1773280100 creator A5044206468 @default.
- W1773280100 creator A5060214405 @default.
- W1773280100 creator A5062258077 @default.
- W1773280100 creator A5069618728 @default.
- W1773280100 creator A5079226006 @default.
- W1773280100 creator A5086113190 @default.
- W1773280100 creator A5086900654 @default.
- W1773280100 date "2015-06-01" @default.
- W1773280100 modified "2023-09-26" @default.
- W1773280100 title "The IRONMAN trial: a protocol for a multicentre randomised placebo-controlled trial of intravenous iron in intensive care unit patients with anaemia." @default.
- W1773280100 cites W2007320066 @default.
- W1773280100 cites W2024428199 @default.
- W1773280100 cites W2036582504 @default.
- W1773280100 cites W2065812098 @default.
- W1773280100 cites W2086626206 @default.
- W1773280100 cites W2101367930 @default.
- W1773280100 cites W2109077832 @default.
- W1773280100 cites W2110604854 @default.
- W1773280100 cites W2117734216 @default.
- W1773280100 cites W2125412761 @default.
- W1773280100 cites W2126707535 @default.
- W1773280100 cites W2132785271 @default.
- W1773280100 cites W2140043294 @default.
- W1773280100 cites W2144758554 @default.
- W1773280100 cites W2165291399 @default.
- W1773280100 cites W2187139009 @default.
- W1773280100 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26080464" @default.
- W1773280100 hasPublicationYear "2015" @default.
- W1773280100 type Work @default.
- W1773280100 sameAs 1773280100 @default.
- W1773280100 citedByCount "7" @default.
- W1773280100 countsByYear W17732801002015 @default.
- W1773280100 countsByYear W17732801002016 @default.
- W1773280100 countsByYear W17732801002017 @default.
- W1773280100 countsByYear W17732801002018 @default.
- W1773280100 crossrefType "posted-content" @default.
- W1773280100 hasAuthorship W1773280100A5007382269 @default.
- W1773280100 hasAuthorship W1773280100A5010197979 @default.
- W1773280100 hasAuthorship W1773280100A5013463984 @default.
- W1773280100 hasAuthorship W1773280100A5016898005 @default.
- W1773280100 hasAuthorship W1773280100A5032363710 @default.
- W1773280100 hasAuthorship W1773280100A5032701736 @default.
- W1773280100 hasAuthorship W1773280100A5034639222 @default.
- W1773280100 hasAuthorship W1773280100A5040469659 @default.
- W1773280100 hasAuthorship W1773280100A5044206468 @default.
- W1773280100 hasAuthorship W1773280100A5060214405 @default.
- W1773280100 hasAuthorship W1773280100A5062258077 @default.
- W1773280100 hasAuthorship W1773280100A5069618728 @default.
- W1773280100 hasAuthorship W1773280100A5079226006 @default.
- W1773280100 hasAuthorship W1773280100A5086113190 @default.
- W1773280100 hasAuthorship W1773280100A5086900654 @default.
- W1773280100 hasConcept C120665830 @default.
- W1773280100 hasConcept C121332964 @default.
- W1773280100 hasConcept C126322002 @default.
- W1773280100 hasConcept C142724271 @default.
- W1773280100 hasConcept C168563851 @default.
- W1773280100 hasConcept C177713679 @default.
- W1773280100 hasConcept C194828623 @default.
- W1773280100 hasConcept C203092338 @default.
- W1773280100 hasConcept C204787440 @default.
- W1773280100 hasConcept C27081682 @default.
- W1773280100 hasConcept C2776376669 @default.
- W1773280100 hasConcept C2780014101 @default.
- W1773280100 hasConcept C2987404301 @default.
- W1773280100 hasConcept C535046627 @default.
- W1773280100 hasConcept C61511704 @default.
- W1773280100 hasConcept C71924100 @default.
- W1773280100 hasConceptScore W1773280100C120665830 @default.
- W1773280100 hasConceptScore W1773280100C121332964 @default.
- W1773280100 hasConceptScore W1773280100C126322002 @default.
- W1773280100 hasConceptScore W1773280100C142724271 @default.
- W1773280100 hasConceptScore W1773280100C168563851 @default.
- W1773280100 hasConceptScore W1773280100C177713679 @default.
- W1773280100 hasConceptScore W1773280100C194828623 @default.
- W1773280100 hasConceptScore W1773280100C203092338 @default.
- W1773280100 hasConceptScore W1773280100C204787440 @default.
- W1773280100 hasConceptScore W1773280100C27081682 @default.
- W1773280100 hasConceptScore W1773280100C2776376669 @default.
- W1773280100 hasConceptScore W1773280100C2780014101 @default.
- W1773280100 hasConceptScore W1773280100C2987404301 @default.
- W1773280100 hasConceptScore W1773280100C535046627 @default.
- W1773280100 hasConceptScore W1773280100C61511704 @default.
- W1773280100 hasConceptScore W1773280100C71924100 @default.
- W1773280100 hasIssue "2" @default.
- W1773280100 hasLocation W17732801001 @default.
- W1773280100 hasOpenAccess W1773280100 @default.
- W1773280100 hasPrimaryLocation W17732801001 @default.
- W1773280100 hasRelatedWork W1979429795 @default.