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- W177411243 abstract "Chlorella 71105, prepared by mass culture techniques, was used in this work. In preliminary studies, young-adult male rats were fed a 21 per cent Chlorella (10 per cent available protein) diet for 110 days with Chlorella as the sole source of protein. The rats appeared normal and healthy, and displayed satisfactory growth. Male weanling rats were fed 92 per cent Chlorella (minerals, vitamins, and agar to make 100 per cent of the ration) for 37 days. These rats also displayed normal appearance and growth rate. The growth of four groups of male weanling littermates fed ad lib. on Chlorella , Chlorella supplemented with 2 per cent L-methionine, casein, and egg protein were compared with a “normal” growth curve. Test rats were fed at 10 per cent available protein level for 7 months and grew in a satisfactory manner. Rats representing “normal” growth were fed a “lab ration” containing 24 per cent crude protein. The rats fed casein weighed an average of 579 gm; those on Chlorella and L-methionine, 453 gm; and those on Chlorella , 402 gm. Chlorella rations were acceptable to rats. Three of 20 weanling rats consuming rations containing Chlorella developed a symmetrical alopecia (loss of hair), which started with the hindquarters and spread over the entire abdomen. A green color appearing on the rats' fur (rats fed Chlorella ) was due simply to external staining by the ration. No gross adverse effects were observed on rats fed Chlorella ; however, histological examinations did reveal some anomalies, particularly in the salivary gland and pancreas of a few of the animals. Further studies will be undertaken in an effort to resolve these provocative histological findings." @default.
- W177411243 created "2016-06-24" @default.
- W177411243 creator A5030418547 @default.
- W177411243 date "1963-01-01" @default.
- W177411243 modified "2023-09-26" @default.
- W177411243 title "Growth and Toxicity Studies on Rats Fed Chlorella 71105" @default.
- W177411243 cites W2285561885 @default.
- W177411243 doi "https://doi.org/10.1016/b978-1-4832-2865-5.50015-4" @default.
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