Matches in SemOpenAlex for { <https://semopenalex.org/work/W1774602174> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1774602174 endingPage "51" @default.
- W1774602174 startingPage "3747" @default.
- W1774602174 abstract "We have identified previously a gene from a human cervical carcinoma cell (HeLa) cDNA expression library that encodes a M(r) approximately 37,000 c-myc promoter-binding protein (MBP-1), which binds to the TATA box sequences of c-myc P2 promoter and exerts a negative regulatory function by down-regulating c-myc expression. In normal human tissues, this cloned gene showed variable expression. In this study, we have demonstrated that introduction of the MBP-1 gene into human breast carcinoma cells reduced their ability to invade through a basement membrane matrix in vitro but did not alter their growth rate. Human breast carcinoma transfected with MBP-1 cells showed a loss of anchorage-independent growth and also suppressed tumor formation in athymic nude mice. These results suggest the possible involvement of MBP-1 as a tumor suppressor gene in human breast carcinoma cells." @default.
- W1774602174 created "2016-06-24" @default.
- W1774602174 creator A5027940255 @default.
- W1774602174 creator A5059592165 @default.
- W1774602174 creator A5061394739 @default.
- W1774602174 creator A5088255915 @default.
- W1774602174 date "1995-09-01" @default.
- W1774602174 modified "2023-09-23" @default.
- W1774602174 title "Human breast carcinoma cells transfected with the gene encoding a c-myc promoter-binding protein (MBP-1) inhibits tumors in nude mice." @default.
- W1774602174 cites W1524240242 @default.
- W1774602174 cites W1589525182 @default.
- W1774602174 cites W1612068869 @default.
- W1774602174 cites W161464813 @default.
- W1774602174 cites W1615513261 @default.
- W1774602174 cites W1881918025 @default.
- W1774602174 cites W1981570640 @default.
- W1774602174 cites W1997328838 @default.
- W1774602174 cites W2007599495 @default.
- W1774602174 cites W2015167444 @default.
- W1774602174 cites W2024247791 @default.
- W1774602174 cites W2130227763 @default.
- W1774602174 cites W2145108148 @default.
- W1774602174 cites W2158145067 @default.
- W1774602174 cites W2158565740 @default.
- W1774602174 cites W2161892290 @default.
- W1774602174 cites W2173601290 @default.
- W1774602174 cites W2411303706 @default.
- W1774602174 cites W2415537889 @default.
- W1774602174 cites W61326834 @default.
- W1774602174 cites W2135532942 @default.
- W1774602174 cites W2470548369 @default.
- W1774602174 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7641187" @default.
- W1774602174 hasPublicationYear "1995" @default.
- W1774602174 type Work @default.
- W1774602174 sameAs 1774602174 @default.
- W1774602174 citedByCount "22" @default.
- W1774602174 countsByYear W17746021742012 @default.
- W1774602174 countsByYear W17746021742013 @default.
- W1774602174 countsByYear W17746021742014 @default.
- W1774602174 countsByYear W17746021742018 @default.
- W1774602174 countsByYear W17746021742019 @default.
- W1774602174 countsByYear W17746021742022 @default.
- W1774602174 crossrefType "journal-article" @default.
- W1774602174 hasAuthorship W1774602174A5027940255 @default.
- W1774602174 hasAuthorship W1774602174A5059592165 @default.
- W1774602174 hasAuthorship W1774602174A5061394739 @default.
- W1774602174 hasAuthorship W1774602174A5088255915 @default.
- W1774602174 hasConcept C104317684 @default.
- W1774602174 hasConcept C121608353 @default.
- W1774602174 hasConcept C150194340 @default.
- W1774602174 hasConcept C153911025 @default.
- W1774602174 hasConcept C187882448 @default.
- W1774602174 hasConcept C2777366897 @default.
- W1774602174 hasConcept C2780278673 @default.
- W1774602174 hasConcept C3018521938 @default.
- W1774602174 hasConcept C502942594 @default.
- W1774602174 hasConcept C530470458 @default.
- W1774602174 hasConcept C54009773 @default.
- W1774602174 hasConcept C54355233 @default.
- W1774602174 hasConcept C81885089 @default.
- W1774602174 hasConcept C86803240 @default.
- W1774602174 hasConceptScore W1774602174C104317684 @default.
- W1774602174 hasConceptScore W1774602174C121608353 @default.
- W1774602174 hasConceptScore W1774602174C150194340 @default.
- W1774602174 hasConceptScore W1774602174C153911025 @default.
- W1774602174 hasConceptScore W1774602174C187882448 @default.
- W1774602174 hasConceptScore W1774602174C2777366897 @default.
- W1774602174 hasConceptScore W1774602174C2780278673 @default.
- W1774602174 hasConceptScore W1774602174C3018521938 @default.
- W1774602174 hasConceptScore W1774602174C502942594 @default.
- W1774602174 hasConceptScore W1774602174C530470458 @default.
- W1774602174 hasConceptScore W1774602174C54009773 @default.
- W1774602174 hasConceptScore W1774602174C54355233 @default.
- W1774602174 hasConceptScore W1774602174C81885089 @default.
- W1774602174 hasConceptScore W1774602174C86803240 @default.
- W1774602174 hasIssue "17" @default.
- W1774602174 hasLocation W17746021741 @default.
- W1774602174 hasOpenAccess W1774602174 @default.
- W1774602174 hasPrimaryLocation W17746021741 @default.
- W1774602174 hasRelatedWork W2017909960 @default.
- W1774602174 hasRelatedWork W2072274286 @default.
- W1774602174 hasRelatedWork W2352440053 @default.
- W1774602174 hasRelatedWork W2356648071 @default.
- W1774602174 hasRelatedWork W2361944476 @default.
- W1774602174 hasRelatedWork W2365822879 @default.
- W1774602174 hasRelatedWork W2371207394 @default.
- W1774602174 hasRelatedWork W2389891941 @default.
- W1774602174 hasRelatedWork W2400063692 @default.
- W1774602174 hasRelatedWork W2612849269 @default.
- W1774602174 hasVolume "55" @default.
- W1774602174 isParatext "false" @default.
- W1774602174 isRetracted "false" @default.
- W1774602174 magId "1774602174" @default.
- W1774602174 workType "article" @default.