FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1774888934> ?p ?o ?g. }

• W1774888934 abstract "Background: This study has used biomarker of exposure-effect continuum to examine the biological characteristics of organophosphate (OP) toxicity and its genotoxic effect among rice farmers. Materials and methods: A cross-sectional study was conducted among 160 pesticide exposed rice farmers and 160 adults from the fishing village as the unexposed group. They share the common socio-economical background for inter-individual comparison in human toxicology assessment. In this study depression of blood cholinesterase is used as a biomarker of exposure to OP toxicity. Two genotoxic assays (micronuclei and comet assay) were conducted as a biomarker of genotoxic effect among the adult population. In this context, m icronuclei assay is used to indicate the chromosome breakage and comet assay to estimate the possible DNA damage. Results: The study showed a significant difference of blood cholinesterase level (p=0.001) between the exposed- unexposed groups. Besides, the results showed that farmers had at least 2-2.5 folds of significant increase (p=0.001) in MN frequency (in 1000 cells) and comet tail length (µm) compared to the unexposed group . In addition, regression analysis among farmers showed that blood cholinesterase level decreased with the genotoxic effects. A small variation (R2=0.148) of MN frequency could be explained by the depression of blood cholinesterase level; however, a significant reduction (p=0. 001), with strong changes (R2=0.712) in comet tail length was attributed to the depression of blood cholinesterase levels. Risk factors like age, body mass index, smoking status and year s of working showed the different strength of the relationship with these genotoxic effects. Conclusions: This study suggests that chronic exposure to OP shows an inhibition to blood cholinesterase level, which is associated with the potential DNA breakage as indicated by comet assay. Aqe, smoking and years of working are the contributing factors influencing the biomarker of effects." @default.
• W1774888934 created "2016-06-24" @default.
• W1774888934 creator A5002727299 @default.
• W1774888934 creator A5003766767 @default.
• W1774888934 creator A5030110420 @default.
• W1774888934 creator A5050981086 @default.
• W1774888934 creator A5057077114 @default.
• W1774888934 creator A5078677060 @default.
• W1774888934 date "2013-01-01" @default.
• W1774888934 modified "2023-10-16" @default.
• W1774888934 title "Biological monitoring of genotoxicity to organophosphate pesticide exposure among rice farmers: Exposure-effect continuum study" @default.
• W1774888934 cites W117197154 @default.
• W1774888934 cites W1491332242 @default.
• W1774888934 cites W1496405210 @default.
• W1774888934 cites W165062961 @default.
• W1774888934 cites W1659912652 @default.
• W1774888934 cites W1967603833 @default.
• W1774888934 cites W1990682206 @default.
• W1774888934 cites W2014201324 @default.
• W1774888934 cites W2016279964 @default.
• W1774888934 cites W2024090761 @default.
• W1774888934 cites W2026002538 @default.
• W1774888934 cites W2039086635 @default.
• W1774888934 cites W2041694332 @default.
• W1774888934 cites W2043611824 @default.
• W1774888934 cites W2044637160 @default.
• W1774888934 cites W2044905037 @default.
• W1774888934 cites W2051047340 @default.
• W1774888934 cites W2051220226 @default.
• W1774888934 cites W2053402932 @default.
• W1774888934 cites W2059433374 @default.
• W1774888934 cites W2068340848 @default.
• W1774888934 cites W2085967479 @default.
• W1774888934 cites W2094156327 @default.
• W1774888934 cites W2095967121 @default.
• W1774888934 cites W2107737844 @default.
• W1774888934 cites W2117920466 @default.
• W1774888934 cites W2120965874 @default.
• W1774888934 cites W2124488275 @default.
• W1774888934 cites W2132886980 @default.
• W1774888934 cites W2136041453 @default.
• W1774888934 cites W2164551609 @default.
• W1774888934 cites W2166553986 @default.
• W1774888934 cites W2331119619 @default.
• W1774888934 cites W2412884438 @default.
• W1774888934 cites W2472172260 @default.
• W1774888934 cites W2484535708 @default.
• W1774888934 cites W2614617925 @default.
• W1774888934 doi "https://doi.org/10.18869/acadpub.johe.2.1.2.27" @default.
• W1774888934 hasPublicationYear "2013" @default.
• W1774888934 type Work @default.
• W1774888934 sameAs 1774888934 @default.
• W1774888934 citedByCount "4" @default.
• W1774888934 countsByYear W17748889342015 @default.
• W1774888934 countsByYear W17748889342016 @default.
• W1774888934 countsByYear W17748889342018 @default.
• W1774888934 countsByYear W17748889342019 @default.
• W1774888934 crossrefType "journal-article" @default.
• W1774888934 hasAuthorship W1774888934A5002727299 @default.
• W1774888934 hasAuthorship W1774888934A5003766767 @default.
• W1774888934 hasAuthorship W1774888934A5030110420 @default.
• W1774888934 hasAuthorship W1774888934A5050981086 @default.
• W1774888934 hasAuthorship W1774888934A5057077114 @default.
• W1774888934 hasAuthorship W1774888934A5078677060 @default.
• W1774888934 hasBestOaLocation W17748889341 @default.
• W1774888934 hasConcept C126322002 @default.
• W1774888934 hasConcept C143425029 @default.
• W1774888934 hasConcept C151730666 @default.
• W1774888934 hasConcept C161176658 @default.
• W1774888934 hasConcept C185592680 @default.
• W1774888934 hasConcept C18903297 @default.
• W1774888934 hasConcept C2776588719 @default.
• W1774888934 hasConcept C2778959862 @default.
• W1774888934 hasConcept C2779343474 @default.
• W1774888934 hasConcept C2780358455 @default.
• W1774888934 hasConcept C2781197716 @default.
• W1774888934 hasConcept C2908647359 @default.
• W1774888934 hasConcept C29730261 @default.
• W1774888934 hasConcept C31896038 @default.
• W1774888934 hasConcept C33070731 @default.
• W1774888934 hasConcept C42407357 @default.
• W1774888934 hasConcept C45080847 @default.
• W1774888934 hasConcept C54355233 @default.
• W1774888934 hasConcept C552990157 @default.
• W1774888934 hasConcept C71924100 @default.
• W1774888934 hasConcept C86803240 @default.
• W1774888934 hasConcept C98274493 @default.
• W1774888934 hasConcept C99454951 @default.
• W1774888934 hasConceptScore W1774888934C126322002 @default.
• W1774888934 hasConceptScore W1774888934C143425029 @default.
• W1774888934 hasConceptScore W1774888934C151730666 @default.
• W1774888934 hasConceptScore W1774888934C161176658 @default.
• W1774888934 hasConceptScore W1774888934C185592680 @default.
• W1774888934 hasConceptScore W1774888934C18903297 @default.
• W1774888934 hasConceptScore W1774888934C2776588719 @default.
• W1774888934 hasConceptScore W1774888934C2778959862 @default.
• W1774888934 hasConceptScore W1774888934C2779343474 @default.
• W1774888934 hasConceptScore W1774888934C2780358455 @default.
• W1774888934 hasConceptScore W1774888934C2781197716 @default.
• W1774888934 hasConceptScore W1774888934C2908647359 @default.

• next