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- W1775179910 startingPage "175" @default.
- W1775179910 abstract "Behavioural disorders in Parkinson's disease can grossly be subdivided in primary disturbances and those which are related to drug treatment. Depression and anxiety are a common feature in parkinsonian patients. Both occur independently of drug treatment. In general, most current antidepressive and anxiolytic drugs could be administered in Parkinson's disease with the same precautions as in the normal population. However, in single case reports modern serotonin reuptake blockers in Parkinson's disease have been accused to worsen parkinsonian motor condition. Combinations of serotonin reuptake inhibitors with MAO-inhibitors like selegiline should be used with caution. In the case of cognitive decline firstly an underlying depression should be disclosed or if existent be treated. Depression seems to be the single most important factor associated with the severity of dementia and early antidepressant treatment seems to decrease cognitive decline in depressed parkinsonian patients. Anticholinergic medications should be discontinued since they may cause mental side effects. Sleep disorders in Parkinson's disease are mainly caused by nocturnal akinesia, which causes sleep fragmentation or altered dreaming and nightmares, which might be a side-effect of dopaminergic treatment. In the first case the administration of a controlled release preparation of levodopa at bedtime may be indicated. If the sleep disorder is considered to be due to dopaminergic medication, a reduction of long-term acting agents like modern dopamine agonists and controlled-release levodopa should be considered. In severe psychotic states related to drug treatment antiparkinsonian therapy must be carefully analysed and, if possible, reduced. If motor condition worsens and/or psychiatric symptoms do not improve, initiation with atypical neuroleptics like clozapine is indicated. The pharmacological and clinical properties of new antipsychotic drugs that can be used in Parkinson's disease are revised." @default.
- W1775179910 created "2016-06-24" @default.
- W1775179910 creator A5041475663 @default.
- W1775179910 creator A5071965708 @default.
- W1775179910 creator A5078689202 @default.
- W1775179910 date "1997-01-01" @default.
- W1775179910 modified "2023-09-26" @default.
- W1775179910 title "Treatment of behavioural disturbances in Parkinson’s disease" @default.
- W1775179910 cites W1820788190 @default.
- W1775179910 cites W1847168837 @default.
- W1775179910 cites W1964329978 @default.
- W1775179910 cites W1964936180 @default.
- W1775179910 cites W1966490500 @default.
- W1775179910 cites W1967579194 @default.
- W1775179910 cites W1968179589 @default.
- W1775179910 cites W1969045963 @default.
- W1775179910 cites W1969579419 @default.
- W1775179910 cites W1969926186 @default.
- W1775179910 cites W1969979364 @default.
- W1775179910 cites W1970075790 @default.
- W1775179910 cites W1972146241 @default.
- W1775179910 cites W1973761685 @default.
- W1775179910 cites W1975445588 @default.
- W1775179910 cites W1975905356 @default.
- W1775179910 cites W1977390419 @default.
- W1775179910 cites W1983366580 @default.
- W1775179910 cites W1983963467 @default.
- W1775179910 cites W1984361059 @default.
- W1775179910 cites W1986392550 @default.
- W1775179910 cites W1986767463 @default.
- W1775179910 cites W1987747889 @default.
- W1775179910 cites W1988477954 @default.
- W1775179910 cites W1988898680 @default.
- W1775179910 cites W1988899383 @default.
- W1775179910 cites W1988986349 @default.
- W1775179910 cites W1989887487 @default.
- W1775179910 cites W1993389023 @default.
- W1775179910 cites W1994955397 @default.
- W1775179910 cites W1995184277 @default.
- W1775179910 cites W1996858839 @default.
- W1775179910 cites W1997023267 @default.
- W1775179910 cites W1997932250 @default.
- W1775179910 cites W2000454212 @default.
- W1775179910 cites W2000628620 @default.
- W1775179910 cites W2000874002 @default.
- W1775179910 cites W2004870459 @default.
- W1775179910 cites W2005983008 @default.
- W1775179910 cites W2006825033 @default.
- W1775179910 cites W2008526565 @default.
- W1775179910 cites W2008560062 @default.
- W1775179910 cites W2009433434 @default.
- W1775179910 cites W2009787453 @default.
- W1775179910 cites W2011832466 @default.
- W1775179910 cites W2013875902 @default.
- W1775179910 cites W2017830194 @default.
- W1775179910 cites W2019953824 @default.
- W1775179910 cites W2022737412 @default.
- W1775179910 cites W2023832139 @default.
- W1775179910 cites W2024452007 @default.
- W1775179910 cites W2025666055 @default.
- W1775179910 cites W2028064682 @default.
- W1775179910 cites W2030187260 @default.
- W1775179910 cites W2034359735 @default.
- W1775179910 cites W2034526026 @default.
- W1775179910 cites W2039091678 @default.
- W1775179910 cites W2040538157 @default.
- W1775179910 cites W2041465605 @default.
- W1775179910 cites W2042478427 @default.
- W1775179910 cites W2042676032 @default.
- W1775179910 cites W2042895504 @default.
- W1775179910 cites W2043816414 @default.
- W1775179910 cites W2044278535 @default.
- W1775179910 cites W2044566539 @default.
- W1775179910 cites W2045279835 @default.
- W1775179910 cites W2045581755 @default.
- W1775179910 cites W2045636903 @default.
- W1775179910 cites W2046098071 @default.
- W1775179910 cites W2046346017 @default.
- W1775179910 cites W2047038801 @default.
- W1775179910 cites W2047328154 @default.
- W1775179910 cites W2048145705 @default.
- W1775179910 cites W2049922305 @default.
- W1775179910 cites W2053098177 @default.
- W1775179910 cites W2053511572 @default.
- W1775179910 cites W2054581670 @default.
- W1775179910 cites W2055352169 @default.
- W1775179910 cites W2055636549 @default.
- W1775179910 cites W2057949003 @default.
- W1775179910 cites W2059230444 @default.
- W1775179910 cites W2060147156 @default.
- W1775179910 cites W2060334759 @default.
- W1775179910 cites W2062134604 @default.
- W1775179910 cites W2064247269 @default.
- W1775179910 cites W2064611362 @default.
- W1775179910 cites W2065733195 @default.
- W1775179910 cites W2067495470 @default.
- W1775179910 cites W2067726982 @default.
- W1775179910 cites W2072850732 @default.