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- W1775281092 abstract "Abstract Background Some nonmotor symptoms may precede the clinical diagnosis of Parkinson's disease (PD) by years. Methods We examined the individual and joint prevalence of depression, daytime sleepiness, and infrequent bowel movement among 10,477 participants of the US National Health and Nutrition Examination Surveys 2005‐2008. Results For all symptoms, the prevalence was higher in women than in men. Importantly, few participants had two or more symptoms: 1.3% at ages 20 to 29, 1.0% at 30 to 39, 1.2% at 40 to 49, 3.5% at 50 to 59, 1.7% at 60 to 69, 1.1% at 70 to 79, and 1.2% at ages 80 years or older in men; the corresponding prevalence in women was 3.1%, 5.2%, 5.7%, 4.1%, 3.1%, 2.3%, and 1.2%, respectively. In both men and women, depression was correlated with infrequent bowel movement and daytime sleepiness, but the latter two were mutually independent. Conclusion The presence of multiple nonmotor symptoms was uncommon in the general population and the prevalence was higher in women than in men. © 2014 International Parkinson and Movement Disorder Society" @default.
- W1775281092 created "2016-06-24" @default.
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- W1775281092 date "2014-07-01" @default.
- W1775281092 modified "2023-09-25" @default.
- W1775281092 title "Individual and joint prevalence of three nonmotor symptoms of PD in the US general population" @default.
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- W1775281092 doi "https://doi.org/10.1002/mds.25950" @default.
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