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- W1776012597 abstract "textabstractIn the intensive Care Unit there is a striking difference between the stateof the art of haemodynamic monitoring and that of pulmonary functionmonitoring. The haemodynamic status of Intensive Care patientsis continuously monitored by devices producing signals of beat-to-beatelectro-cardiograms and blood pressures, using sophisticated, fully developeddevices, that can be delivered from stock and handled with ease bypeople without special technical background. The resulting signals areavailable in real-time) and the interpretation of the signal is based onphysiologic models. On the other hand, pulmonary monitoring is usuallylimited to a few blood gas measurements per day, occasional chest X-rayand occasional inspection of airway pressures. These simple data are notsufficient to describe properties of the lung and the gas transport, andindicate deterioration of the lung function only at a very late stage, whenthe chances for complications have already been increased. It also meansthat in mechanically ventilated patients the clinician takes the control ofthe ventilation over from the patient without having direct informationon the gas exchange process in the lung. Instead the clinician has to relyon secondary information like blood gas pressure. In most cases thesetechniques give adequate information. However, e.g. in patients sufferingthe Adult Respiratory Distress Syndrome the clinician tries to maintainthe lung volume at a desired level by application of a positive airwaypressure (PEEP, Positive End-Expiratory Pressure), but is not able tomeasure the lung volume that he wants to control.This thesis reports on the development and validation of a multiplebreath indicator gas wash-out system to measure the lung volumeand ventilation inhomogeneity during mechanical ventilation." @default.
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- W1776012597 date "1994-04-13" @default.
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- W1776012597 title "Measurement of lung volume and an index of ventilation inhomogeneity during mechanical ventilation" @default.
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