FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1776598191> ?p ?o ?g. }

• W1776598191 endingPage "6104" @default.
• W1776598191 startingPage "6095" @default.
• W1776598191 abstract "Abstract The phenomenon of concomitant tumor immunity involves a tumor-bearing host rejecting another similar tumor at a distant site and suggests the existence of tumor-specific immunity. Loss of this immunity may contribute to tumor metastasis. However, mechanisms underlying the loss of concomitant immunity are largely unknown. We set up a concomitant tumor immunity model in which this immunity is gradually lost as the primary tumor progresses. We found that CD8+ T cells, especially tumor-infiltrating CD8+ T cells, from mice that lost concomitant tumor immunity, possessed potent antitumor properties and strongly expressed effector molecules. Furthermore, effector/memory regulatory T cells (Treg cells, CD103+CD4+Foxp3+ T cells) increased as the primary tumor progressed. They initially accumulated around the tumor and in the spleen at later points. Not only did these cells more greatly express killing molecules, they also suppressed the functions of tumor-bearing CD8+ T cells in vitro and in vivo. Finally, we show that these effector/memory Treg cells inhibit concomitant tumor immunity in vivo. Taken together, data suggest that effector/memory Treg cells are responsible for the loss of concomitant tumor immunity associated with tumor progression." @default.
• W1776598191 created "2016-06-24" @default.
• W1776598191 creator A5001390997 @default.
• W1776598191 creator A5016677799 @default.
• W1776598191 creator A5034399195 @default.
• W1776598191 creator A5050411361 @default.
• W1776598191 creator A5055361534 @default.
• W1776598191 creator A5075469418 @default.
• W1776598191 creator A5076142094 @default.
• W1776598191 creator A5090939559 @default.
• W1776598191 date "2009-05-15" @default.
• W1776598191 modified "2023-10-18" @default.
• W1776598191 title "Effector/Memory but Not Naive Regulatory T Cells Are Responsible for the Loss of Concomitant Tumor Immunity" @default.
• W1776598191 cites W1481185457 @default.
• W1776598191 cites W1501511128 @default.
• W1776598191 cites W1530044612 @default.
• W1776598191 cites W1661359408 @default.
• W1776598191 cites W1916627441 @default.
• W1776598191 cites W1984484036 @default.
• W1776598191 cites W1990854674 @default.
• W1776598191 cites W1992986960 @default.
• W1776598191 cites W1997577538 @default.
• W1776598191 cites W2002774826 @default.
• W1776598191 cites W2013548919 @default.
• W1776598191 cites W2014540704 @default.
• W1776598191 cites W2024263435 @default.
• W1776598191 cites W2033695252 @default.
• W1776598191 cites W2066899488 @default.
• W1776598191 cites W2066964346 @default.
• W1776598191 cites W2068521142 @default.
• W1776598191 cites W2089828715 @default.
• W1776598191 cites W2093608608 @default.
• W1776598191 cites W2095403983 @default.
• W1776598191 cites W2097074641 @default.
• W1776598191 cites W2100989466 @default.
• W1776598191 cites W2105017308 @default.
• W1776598191 cites W2105459360 @default.
• W1776598191 cites W2107336310 @default.
• W1776598191 cites W2108940390 @default.
• W1776598191 cites W2110502611 @default.
• W1776598191 cites W2113030185 @default.
• W1776598191 cites W2114200189 @default.
• W1776598191 cites W2123105952 @default.
• W1776598191 cites W2126072190 @default.
• W1776598191 cites W2126091327 @default.
• W1776598191 cites W2129047107 @default.
• W1776598191 cites W2131778873 @default.
• W1776598191 cites W2132207342 @default.
• W1776598191 cites W2132207502 @default.
• W1776598191 cites W2140633375 @default.
• W1776598191 cites W2147784618 @default.
• W1776598191 cites W2148806075 @default.
• W1776598191 cites W2148911309 @default.
• W1776598191 cites W2150678612 @default.
• W1776598191 cites W2160117150 @default.
• W1776598191 cites W2170817965 @default.
• W1776598191 cites W2320254486 @default.
• W1776598191 cites W2335365056 @default.
• W1776598191 cites W4211174180 @default.
• W1776598191 doi "https://doi.org/10.4049/jimmunol.0803829" @default.
• W1776598191 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19414761" @default.
• W1776598191 hasPublicationYear "2009" @default.
• W1776598191 type Work @default.
• W1776598191 sameAs 1776598191 @default.
• W1776598191 citedByCount "44" @default.
• W1776598191 countsByYear W17765981912012 @default.
• W1776598191 countsByYear W17765981912013 @default.
• W1776598191 countsByYear W17765981912014 @default.
• W1776598191 countsByYear W17765981912015 @default.
• W1776598191 countsByYear W17765981912016 @default.
• W1776598191 countsByYear W17765981912017 @default.
• W1776598191 countsByYear W17765981912018 @default.
• W1776598191 countsByYear W17765981912019 @default.
• W1776598191 countsByYear W17765981912020 @default.
• W1776598191 countsByYear W17765981912021 @default.
• W1776598191 countsByYear W17765981912022 @default.
• W1776598191 countsByYear W17765981912023 @default.
• W1776598191 crossrefType "journal-article" @default.
• W1776598191 hasAuthorship W1776598191A5001390997 @default.
• W1776598191 hasAuthorship W1776598191A5016677799 @default.
• W1776598191 hasAuthorship W1776598191A5034399195 @default.
• W1776598191 hasAuthorship W1776598191A5050411361 @default.
• W1776598191 hasAuthorship W1776598191A5055361534 @default.
• W1776598191 hasAuthorship W1776598191A5075469418 @default.
• W1776598191 hasAuthorship W1776598191A5076142094 @default.
• W1776598191 hasAuthorship W1776598191A5090939559 @default.
• W1776598191 hasBestOaLocation W17765981911 @default.
• W1776598191 hasConcept C126322002 @default.
• W1776598191 hasConcept C154317977 @default.
• W1776598191 hasConcept C167672396 @default.
• W1776598191 hasConcept C202751555 @default.
• W1776598191 hasConcept C203014093 @default.
• W1776598191 hasConcept C2779341262 @default.
• W1776598191 hasConcept C2779384505 @default.
• W1776598191 hasConcept C2779727006 @default.
• W1776598191 hasConcept C502942594 @default.
• W1776598191 hasConcept C51785407 @default.
• W1776598191 hasConcept C55493867 @default.

• next