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• W1777753509 startingPage "1389" @default.
• W1777753509 abstract "Objectives The goal of this work was to obtain and evaluate measurements of tissue sound speed in the breast, particularly dense breasts, using backscatter ultrasound tomography. Methods An automated volumetric breast ultrasound scanner was constructed for imaging the prone patient. A 5- to 7-MHz linear array transducer acquired 17,920 radiofrequency pulse echo A-lines from the breast, and a back-wall reflector rotated over 360° in 25 seconds. Sound speed images used reflector echoes that after preprocessing were uploaded into a graphics processing unit for filtered back-projection reconstruction. A velocimeter also was constructed to measure the sound speed and attenuation for comparison to scanner performance. Measurements were made using the following: (1) deionized water from 22°C to 90°C; (2) various fluids with sound speeds from 1240 to 1904 m/s; (3) acrylamide gel test objects with features from 1 to 15 mm in diameter; and (4) healthy volunteers. Results The mean error ± SD between sound speed reference and image data was −0.48% ± 9.1%, and the error between reference and velocimeter measurements was −1.78% ± 6.50%. Sound speed image and velocimeter measurements showed a difference of 0.10% ± 4.04%. Temperature data showed a difference between theory and imaging performance of −0.28% ± 0.22%. Images of polyacrylamide test objects showed detectability of an approximately 1% sound speed difference in a 2.4-mm cylindrical inclusion with a contrast to noise ratio of 7.9 dB. Conclusions An automated breast scanner offers the potential to make consistent automated tomographic images of breast backscatter, sound speed, and attenuation, potentially improving diagnosis, particularly in dense breasts." @default.
• W1777753509 created "2016-06-24" @default.
• W1777753509 creator A5044687924 @default.
• W1777753509 creator A5083642980 @default.
• W1777753509 date "2012-09-01" @default.
• W1777753509 modified "2023-10-16" @default.
• W1777753509 title "Imaging of Sound Speed Using Reflection Ultrasound Tomography" @default.
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• W1777753509 doi "https://doi.org/10.7863/jum.2012.31.9.1389" @default.
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