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• W1779366965 abstract "The location of coproporphyrinogen III oxidase in mitochondria was studied in rat liver by using the digitonin method or hypo-osmotic media for fractionation. The enzyme was found in the intermembrane space with a fraction loosely bound to the inner membrane. This fraction was released by washing the inner-membrane-matrix complex with alkaline solutions or solutions of high ionic strength. The enzyme in both fractions had the same Km (0.16 micrometer) for coproporphyrinogen III. When incubation was performed in a medium that avoided destruction of enzyme membrane binding, a dramatic increase in activity was observed after sonication of whole mitochondria or of the inner-membrane-matrix complex." @default.
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• W1779366965 date "1978-10-15" @default.
• W1779366965 modified "2023-10-03" @default.
• W1779366965 title "The mitochondrial localization of coproporphyrinogen III oxidase" @default.
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• W1779366965 doi "https://doi.org/10.1042/bj1760097" @default.
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