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- W1779667043 abstract "Management decisions for patients with prostate cancer present a dilemma for both patients and their clinicians because prostate cancers demonstrate a wide range in biologic activity, with the majority of cases not leading to a prostate cancer related death. Furthermore, the current treatment optio ns have significant side effects, such as incontinence, rectal injury and impotence. Key elements for guiding appropriate treatment include: distinction of organ-confined disease from extracapsular extension (ECE); and determination of tumor volume and tumor grade, none of which have been satisfactorily accomplished in today's pre-treatment paradigm. Magnetic resonance imaging (MRI) has the capability to assess prostate tissue, both functionally and morphologically. MRI as a staging tool has not shown enough consistency or sufficient accuracy for widespread adoption in clinical practice; yet, recent technical developments in MRI have yielded improved results. At our institution we have combined the use of new endorectal 3 Tesla MRI technology, T2-weighted, and high spatial resolution dynamic-contrast enhanced (DCE) MRI to non-invasively assess the prostate with higher signal-to-noise ratio and spatial resolution than previously achieved. This approach allows assessment of prostate-tissue morphology and kinetics, thus providing a non-invasive tool for tumor detection and staging and, consequently, directing biopsy and treatment specifically to diseased areas for a pre-treatment evaluation that can assist in the rational selection of patients for appropriate prostate cancer therapy." @default.
- W1779667043 created "2016-06-24" @default.
- W1779667043 creator A5018711422 @default.
- W1779667043 creator A5064959639 @default.
- W1779667043 creator A5086139759 @default.
- W1779667043 date "2008-11-04" @default.
- W1779667043 modified "2023-09-23" @default.
- W1779667043 title "The role of magnetic resonance imaging (MRI) in prostate cancer imaging and staging at 1.5 and 3 Tesla: The Beth Israel Deaconess Medical Center (BIDMC) approach" @default.
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- W1779667043 doi "https://doi.org/10.3233/cbm-2008-44-507" @default.
- W1779667043 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2739836" @default.
- W1779667043 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18957714" @default.
- W1779667043 hasPublicationYear "2008" @default.
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