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• W1780497578 abstract "Pestiviruses are some of the most significant pathogens affecting ruminants and swine. Here, we assembled a 11 276 bp contig encoding a predicted 3635 aa polyprotein from porcine serum with 68 % pairwise identity to that of a recently partially characterized Rhinolophus affinis pestivirus (RaPV) and approximately 25-28 % pairwise identity to those of other pestiviruses. The virus was provisionally named atypical porcine pestivirus (APPV). Metagenomic sequencing of 182 serum samples identified four additional APPV-positive samples. Positive samples originated from five states and ELISAs using recombinant APPV Erns found cross-reactive antibodies in 94 % of a collection of porcine serum samples, suggesting widespread distribution of APPV in the US swine herd. The molecular and serological results suggest that APPV is a novel, highly divergent porcine pestivirus widely distributed in US pigs." @default.
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• W1780497578 date "2015-10-01" @default.
• W1780497578 modified "2023-10-16" @default.
• W1780497578 title "Discovery of a novel putative atypical porcine pestivirus in pigs in the USA" @default.
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• W1780497578 doi "https://doi.org/10.1099/jgv.0.000251" @default.
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