FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1781252183> ?p ?o ?g. }

• W1781252183 abstract "Advancements in the micro-and nano-scale fabrication techniques have opened up new avenues for the development of portable, scalable and easier-to-use biosensors. Over the last few years, electrodes made of carbon have been widely used as sensing units in biosensors due to their attractive physiochemical properties. The aim of this research is to investigate different strategies to develop functionalized high surface carbon micro/nano-structures for electrochemical and biosensing devices. High aspect ratio three-dimensional carbon microarrays were fabricated via carbon microelectromechanical systems (C-MEMS) technique, which is based on pyrolyzing pre-patterned organic photoresist polymers. To further increase the surface area of the carbon microstructures, surface porosity was introduced by two strategies, i.e. (i) using F127 as porogen and (ii) oxygen reactive ion etch (RIE) treatment. Electrochemical characterization showed that porous carbon thin film electrodes prepared by using F127 as porogen had an effective surface area (Aeff 185%) compared to the conventional carbon electrode. To achieve enhanced electrochemical sensitivity for C-MEMS based functional devices, graphene was conformally coated onto high aspect ratio three-dimensional (3D) carbon micropillar arrays using electrostatic spray deposition (ESD) technique. The amperometric response of graphene/carbon micropillar electrode arrays exhibited higher electrochemical activity, improved charge transfer and a linear response towards H2O2 detection between 250μM to 5.5mM. Furthermore, carbon structures with dimensions from 50 nano-to micrometer level have been fabricated by pyrolyzing photo-nanoimprint lithography patterned organic resist polymer. Microstructure, elemental composition and resistivity characterization of the carbon nanostructures produced by this process were very similar to conventional photoresist derived carbon. Surface functionalization of the carbon nanostructures was performed using direct amination technique. Considering the need for requisite functional groups to covalently attach bioreceptors on the carbon surface for biomolecule detection, different oxidation techniques were compared to study the types of carbon–oxygen groups formed on the surface and their percentages with respect to different oxidation pretreatment times. Finally, a label-free detection strategy using signaling aptamer/protein binding complex for platelet-derived growth factor oncoprotein detection on functionalized three-dimensional carbon microarrays platform was demonstrated. The sensor showed near linear relationship between the relative fluorescence difference and protein concentration even in the sub-nanomolar range with an excellent detection limit of 5 pmol." @default.
• W1781252183 created "2016-06-24" @default.
• W1781252183 creator A5025262752 @default.
• W1781252183 date "2017-11-13" @default.
• W1781252183 modified "2023-10-18" @default.
• W1781252183 title "Functionalized Carbon Micro/Nanostructures for Biomolecular Detection" @default.
• W1781252183 cites W11476871 @default.
• W1781252183 cites W178410160 @default.
• W1781252183 cites W1989745389 @default.
• W1781252183 cites W1991733198 @default.
• W1781252183 cites W1994168728 @default.
• W1781252183 cites W1995763457 @default.
• W1781252183 cites W1997084181 @default.
• W1781252183 cites W1997163562 @default.
• W1781252183 cites W1997534260 @default.
• W1781252183 cites W1999782533 @default.
• W1781252183 cites W2001642272 @default.
• W1781252183 cites W2007576784 @default.
• W1781252183 cites W2008695809 @default.
• W1781252183 cites W2011379198 @default.
• W1781252183 cites W2018027818 @default.
• W1781252183 cites W2021742988 @default.
• W1781252183 cites W2028157562 @default.
• W1781252183 cites W2028908307 @default.
• W1781252183 cites W2031670446 @default.
• W1781252183 cites W2032793448 @default.
• W1781252183 cites W2041400078 @default.
• W1781252183 cites W2043066580 @default.
• W1781252183 cites W2054115296 @default.
• W1781252183 cites W2058122340 @default.
• W1781252183 cites W2058272047 @default.
• W1781252183 cites W2071074002 @default.
• W1781252183 cites W2071371484 @default.
• W1781252183 cites W2073216203 @default.
• W1781252183 cites W2073812558 @default.
• W1781252183 cites W2074483474 @default.
• W1781252183 cites W2074684620 @default.
• W1781252183 cites W2078839213 @default.
• W1781252183 cites W2079321730 @default.
• W1781252183 cites W2086189444 @default.
• W1781252183 cites W2093421311 @default.
• W1781252183 cites W2101312334 @default.
• W1781252183 cites W2104525153 @default.
• W1781252183 cites W2105348088 @default.
• W1781252183 cites W2110778612 @default.
• W1781252183 cites W2115669216 @default.
• W1781252183 cites W2115762575 @default.
• W1781252183 cites W2122271644 @default.
• W1781252183 cites W2124391417 @default.
• W1781252183 cites W2129589778 @default.
• W1781252183 cites W2134432028 @default.
• W1781252183 cites W2136334331 @default.
• W1781252183 cites W2136818943 @default.
• W1781252183 cites W2143627748 @default.
• W1781252183 cites W2146082910 @default.
• W1781252183 cites W2168985622 @default.
• W1781252183 cites W2327321414 @default.
• W1781252183 cites W2332433553 @default.
• W1781252183 cites W2561503622 @default.
• W1781252183 cites W2624602067 @default.
• W1781252183 cites W596603678 @default.
• W1781252183 cites W623603877 @default.
• W1781252183 cites W636847917 @default.
• W1781252183 doi "https://doi.org/10.25148/etd.fi12112702" @default.
• W1781252183 hasPublicationYear "2017" @default.
• W1781252183 type Work @default.
• W1781252183 sameAs 1781252183 @default.
• W1781252183 citedByCount "0" @default.
• W1781252183 crossrefType "dissertation" @default.
• W1781252183 hasAuthorship W1781252183A5025262752 @default.
• W1781252183 hasBestOaLocation W17812521831 @default.
• W1781252183 hasConcept C104779481 @default.
• W1781252183 hasConcept C134406635 @default.
• W1781252183 hasConcept C140205800 @default.
• W1781252183 hasConcept C147789679 @default.
• W1781252183 hasConcept C159985019 @default.
• W1781252183 hasConcept C160756335 @default.
• W1781252183 hasConcept C171250308 @default.
• W1781252183 hasConcept C17525397 @default.
• W1781252183 hasConcept C185592680 @default.
• W1781252183 hasConcept C192562407 @default.
• W1781252183 hasConcept C2779227376 @default.
• W1781252183 hasConcept C30080830 @default.
• W1781252183 hasConcept C37977207 @default.
• W1781252183 hasConcept C513720949 @default.
• W1781252183 hasConceptScore W1781252183C104779481 @default.
• W1781252183 hasConceptScore W1781252183C134406635 @default.
• W1781252183 hasConceptScore W1781252183C140205800 @default.
• W1781252183 hasConceptScore W1781252183C147789679 @default.
• W1781252183 hasConceptScore W1781252183C159985019 @default.
• W1781252183 hasConceptScore W1781252183C160756335 @default.
• W1781252183 hasConceptScore W1781252183C171250308 @default.
• W1781252183 hasConceptScore W1781252183C17525397 @default.
• W1781252183 hasConceptScore W1781252183C185592680 @default.
• W1781252183 hasConceptScore W1781252183C192562407 @default.
• W1781252183 hasConceptScore W1781252183C2779227376 @default.
• W1781252183 hasConceptScore W1781252183C30080830 @default.
• W1781252183 hasConceptScore W1781252183C37977207 @default.
• W1781252183 hasConceptScore W1781252183C513720949 @default.
• W1781252183 hasLocation W17812521831 @default.

• next