FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1781282175> ?p ?o ?g. }

• W1781282175 endingPage "825" @default.
• W1781282175 startingPage "819" @default.
• W1781282175 abstract "Monoamine oxidases (MAOs) have recently emerged as important mitochondrial sources of oxidative stress in the cardiovascular system. Generation of reactive oxygen species during the brief episodes of ischemic preconditioning (IPC) is responsible for the cardioprotection at reperfusion. The aim of this study was to assess the effects of two MAO inhibitors (clorgyline and pargyline) on the IPC-related protection in isolated rat hearts. Animals subjected to 30 min global ischemia and 120 min reperfusion were assigned to the following groups: (i) Control, no additional intervention; (ii) IPC, 3 cycles of 5 min ischemia and 5 min reperfusion before the index ischemia; (iii) IPC-clorgyline, IPC protocol bracketed for 5 min with clorgyline (50 μmol/L); (iv) IPC-pargyline, IPC protocol bracketed for 5 min with pargyline (0.5 mmol/L). The postischemic functional recovery was assessed by the left ventricular developed pressure (LVDP) and the indices of contractility (+dLVP/dt max) and relaxation (-dLVP/dt max). Infarct size (IS) was quantified by TTC staining. In both genders, IPC significantly improved functional recovery that was further enhanced in the presence of either clorgyline or pargyline. IS reduction was comparable among all the preconditioned groups, regardless of the presence of MAO inhibitors. In isolated rat hearts, acute inhibition of MAOs potentiates the IPC-induced postischemic functional recovery without interfering with the anti-necrotic protection." @default.
• W1781282175 created "2016-06-24" @default.
• W1781282175 creator A5011386859 @default.
• W1781282175 creator A5043770843 @default.
• W1781282175 creator A5044162050 @default.
• W1781282175 creator A5066407630 @default.
• W1781282175 creator A5068037083 @default.
• W1781282175 creator A5073926564 @default.
• W1781282175 creator A5074663388 @default.
• W1781282175 creator A5077503019 @default.
• W1781282175 date "2015-09-01" @default.
• W1781282175 modified "2023-10-18" @default.
• W1781282175 title "Acute inhibition of monoamine oxidase and ischemic preconditioning in isolated rat hearts: interference with postischemic functional recovery but no effect on infarct size reduction" @default.
• W1781282175 cites W1523213544 @default.
• W1781282175 cites W1960065666 @default.
• W1781282175 cites W1986592002 @default.
• W1781282175 cites W1999220821 @default.
• W1781282175 cites W2000800148 @default.
• W1781282175 cites W2000864465 @default.
• W1781282175 cites W2000949542 @default.
• W1781282175 cites W2004489470 @default.
• W1781282175 cites W2004886717 @default.
• W1781282175 cites W2005103288 @default.
• W1781282175 cites W2006084919 @default.
• W1781282175 cites W2008235034 @default.
• W1781282175 cites W2014649168 @default.
• W1781282175 cites W2021211288 @default.
• W1781282175 cites W2024770800 @default.
• W1781282175 cites W2030586784 @default.
• W1781282175 cites W2033858209 @default.
• W1781282175 cites W2035239732 @default.
• W1781282175 cites W2042354162 @default.
• W1781282175 cites W2043081679 @default.
• W1781282175 cites W2046592449 @default.
• W1781282175 cites W2047003111 @default.
• W1781282175 cites W2054475515 @default.
• W1781282175 cites W2056117281 @default.
• W1781282175 cites W2057663635 @default.
• W1781282175 cites W2059391512 @default.
• W1781282175 cites W2067071865 @default.
• W1781282175 cites W2078485844 @default.
• W1781282175 cites W2086332600 @default.
• W1781282175 cites W2088727965 @default.
• W1781282175 cites W2091834373 @default.
• W1781282175 cites W2112063935 @default.
• W1781282175 cites W2122501550 @default.
• W1781282175 cites W2126311981 @default.
• W1781282175 cites W2130084088 @default.
• W1781282175 cites W2138567940 @default.
• W1781282175 cites W2142456895 @default.
• W1781282175 cites W2144640999 @default.
• W1781282175 cites W2145047965 @default.
• W1781282175 cites W2146217294 @default.
• W1781282175 cites W2153327865 @default.
• W1781282175 cites W2154275417 @default.
• W1781282175 cites W2164394675 @default.
• W1781282175 cites W2169166924 @default.
• W1781282175 cites W2172487604 @default.
• W1781282175 cites W2885565899 @default.
• W1781282175 cites W4376477343 @default.
• W1781282175 doi "https://doi.org/10.1139/cjpp-2015-0103" @default.
• W1781282175 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26322912" @default.
• W1781282175 hasPublicationYear "2015" @default.
• W1781282175 type Work @default.
• W1781282175 sameAs 1781282175 @default.
• W1781282175 citedByCount "6" @default.
• W1781282175 countsByYear W17812821752016 @default.
• W1781282175 countsByYear W17812821752017 @default.
• W1781282175 countsByYear W17812821752018 @default.
• W1781282175 countsByYear W17812821752021 @default.
• W1781282175 countsByYear W17812821752023 @default.
• W1781282175 crossrefType "journal-article" @default.
• W1781282175 hasAuthorship W1781282175A5011386859 @default.
• W1781282175 hasAuthorship W1781282175A5043770843 @default.
• W1781282175 hasAuthorship W1781282175A5044162050 @default.
• W1781282175 hasAuthorship W1781282175A5066407630 @default.
• W1781282175 hasAuthorship W1781282175A5068037083 @default.
• W1781282175 hasAuthorship W1781282175A5073926564 @default.
• W1781282175 hasAuthorship W1781282175A5074663388 @default.
• W1781282175 hasAuthorship W1781282175A5077503019 @default.
• W1781282175 hasConcept C126322002 @default.
• W1781282175 hasConcept C181199279 @default.
• W1781282175 hasConcept C185592680 @default.
• W1781282175 hasConcept C2776024655 @default.
• W1781282175 hasConcept C2777067607 @default.
• W1781282175 hasConcept C2779311647 @default.
• W1781282175 hasConcept C2779676291 @default.
• W1781282175 hasConcept C2910293678 @default.
• W1781282175 hasConcept C39133596 @default.
• W1781282175 hasConcept C42219234 @default.
• W1781282175 hasConcept C541997718 @default.
• W1781282175 hasConcept C55493867 @default.
• W1781282175 hasConcept C71924100 @default.
• W1781282175 hasConcept C98274493 @default.
• W1781282175 hasConceptScore W1781282175C126322002 @default.
• W1781282175 hasConceptScore W1781282175C181199279 @default.
• W1781282175 hasConceptScore W1781282175C185592680 @default.
• W1781282175 hasConceptScore W1781282175C2776024655 @default.

• next