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• W1781447617 startingPage "3076" @default.
• W1781447617 abstract "Cascade cyclization of a 3-[(3-methylbut-2-enylamino)methyl]but-3-en-1-ol derivative with aldehydes in the presence of TMSOTf at 0 °C under mild conditions provides the corresponding spiropyrrolidine scaffolds in good yields. Similar cyclization of a 3-[(4-methylpent-3-enylamino)methyl]but-3-en-1-ol derivative with aldehydes affords the correponding spiropiperidine compounds. This is a new approach for the construction of biologically relevant spirocycles in a single-step process." @default.
• W1781447617 created "2016-06-24" @default.
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• W1781447617 date "2015-04-02" @default.
• W1781447617 modified "2023-09-24" @default.
• W1781447617 title "Tandem Prins Strategy for the Synthesis of Spiropyrrolidine and Spiropiperidine Derivatives" @default.
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• W1781447617 doi "https://doi.org/10.1002/ejoc.201500215" @default.
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