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- W1781753337 abstract "Background: Data on the mortality of H 1 N 1 pneumonia among patients admitted in the Intensive Care Unit (ICU) vary. Aim: To describe the characteristics of the adult patients who were admitted in three ICUs of a major Greek hospital due to H 1 N 1 virus pneumonia and to identify predictors of survival. Methods: 25 patients with H 1 N 1 pneumonia (72% male; 28% female; 49.7±15 years old) who were admitted in the ICU between October 2009 and February 2011, were retsrospectively studied. Severity of disease scores, comorbidities, disease complications, time of diagnosis and treatment effect were recorded. Mann-Whitney test and x 2 test were used for statistical comparisons. Results: At ICU admission, APACHE II score and CURB-65 score were 15.8±4.9 and 2.4±0.9 correspondingly, while 40% of patients presented with ≥2 major complications (ARDS, acute renal failure, myocardial ischemia or shock). Obesity, immunocompromise, coronary heart disease and diabetes mellitus were present in 36%, 32%, 24% and 24% of patients correspondingly, while 44% of them were smokers. The detection of pharyngeal smear antigen took place in 5.5±3.7 days, oseltamivir initiation in 6.2±3.9 days and ICU admission in 7.3±6.8 days, since the establishment of the disease. H 1 N 1 infection was fatal for 72% of patients.The improvement of the radiologic pattern after oseltamivir initiation (p Conclusions: The mortality of patients admitted in ICU due to H 1 N 1 virus pneumonia was high. Although oseltamivir administration was beneficial in some cases, there was a delay in the diagnosis of the disease and the initiation of treatment." @default.
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- W1781753337 date "2011-09-01" @default.
- W1781753337 modified "2023-09-24" @default.
- W1781753337 title "Prognostic factors of survival among adult patients admitted in the ICU due to severe H1N1 pneumonia" @default.
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