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- W1782442555 abstract "Objective . Cancer-related fatigue (CRF) is the most common and devastating problem in cancer patients even after successful treatment. This study aimed to determine the effects of supervised multimodal exercise interventions on cancer-related fatigue through a systematic review and meta-analysis. Design . A systematic review was conducted to determine the effectiveness of multimodal exercise interventions on CRF. Databases of PubMed, CENTRAL, EMBASE, and OVID were searched between January and March 2014 to retrieve randomized controlled trials. Risk of bias was evaluated using the PEDro scale. Results . Nine studies<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mrow><mml:mfenced separators=|><mml:mrow><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>772</mml:mn></mml:mrow></mml:mfenced></mml:mrow></mml:math>were included in both systematic review and meta-analysis. Multimodal interventions including aerobic exercise, resistance training, and stretching improved CRF symptoms (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:mtext>SMD</mml:mtext><mml:mo>=</mml:mo><mml:mo>-</mml:mo><mml:mn>0.23</mml:mn></mml:math>; 95% CI: −0.37 to −0.09;<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M3><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.001</mml:mn></mml:math>). These effects were also significant in patients undergoing chemotherapy<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M4><mml:mrow><mml:mfenced separators=|><mml:mrow><mml:mi>P</mml:mi><mml:mo><</mml:mo><mml:mn>0.0001</mml:mn></mml:mrow></mml:mfenced></mml:mrow></mml:math>. Nonsignificant differences were found for resistance training interventions<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M5><mml:mrow><mml:mfenced separators=|><mml:mrow><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.30</mml:mn></mml:mrow></mml:mfenced></mml:mrow></mml:math>. Slight evidence of publication bias was observed<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M6><mml:mrow><mml:mfenced separators=|><mml:mrow><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.04</mml:mn></mml:mrow></mml:mfenced></mml:mrow></mml:math>. The studies had a low risk of bias (PEDro scale mean score of 6.4 (standard deviation (SD) ± 1.0)). Conclusion . Supervised multimodal exercise interventions including aerobic, resistance, and stretching exercises are effective in controlling CRF. These findings suggest that these exercise protocols should be included as a crucial part of the rehabilitation programs for cancer survivors and patients during anticancer treatments." @default.
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- W1782442555 date "2015-01-01" @default.
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- W1782442555 title "Effects of Supervised Multimodal Exercise Interventions on Cancer-Related Fatigue: Systematic Review and Meta-Analysis of Randomized Controlled Trials" @default.
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- W1782442555 doi "https://doi.org/10.1155/2015/328636" @default.
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