Matches in SemOpenAlex for { <https://semopenalex.org/work/W1782652550> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W1782652550 endingPage "202" @default.
- W1782652550 startingPage "1197" @default.
- W1782652550 abstract "Prediction of chemotherapy response is still a problem in oncological patients.Studies with PET and 18F-fluorouracil (FU) were used for measurements of drug concentrations in patients with liver metastases from colorectal carcinoma. The PET data obtained before onset of FU chemotherapy were correlated to the growth rate of the metastases after therapy. The final evaluation included 25 metastases obtained in 17 patients. CT preceded the first chemotherapeutic cycle and was repeated within 3-11 mo after onset of treatment. The uptake of the cytostatic agent was evaluated in the liver metastases using the SUV at 120 min after tracer infusion. Tumor growth rate of the metastases was calculated based on CT volumetric data.The trapping of 18F-FU was highly variable even for multiple metastases in the same patients. Six metastases with high 18F-FU uptake values exceeding 3.0 SUV correlated with negative growth rate values, 5 of 25 metastases with intermediate uptake values ranging from 2.0-3.0 SUV were associated with almost stable growth rate values nearly zero and 14 of 25 metastases with low uptake values <2.0 SUV demonstrated positive growth rate values. Only metastases with a 18F-FU uptake exceeding 3.0 SUV at 120 min postinjection demonstrated a response to therapy. A significant correlation of 0.86 (p < 0.001) was found between the 18F-FU uptake values in the metastases measured before chemotherapy and the growth rate of the lesions after treatment.The data show, that FU chemotherapy outcome can be predicted using a single PET study with 18F-FU before onset to therapy." @default.
- W1782652550 created "2016-06-24" @default.
- W1782652550 creator A5008622761 @default.
- W1782652550 creator A5011887107 @default.
- W1782652550 creator A5046601855 @default.
- W1782652550 creator A5049419102 @default.
- W1782652550 creator A5066125769 @default.
- W1782652550 creator A5079389598 @default.
- W1782652550 creator A5087307905 @default.
- W1782652550 date "1998-07-01" @default.
- W1782652550 modified "2023-09-26" @default.
- W1782652550 title "Fluorine-18-fluorouracil to predict therapy response in liver metastases from colorectal carcinoma." @default.
- W1782652550 cites W1554810720 @default.
- W1782652550 cites W158134230 @default.
- W1782652550 cites W1766290423 @default.
- W1782652550 cites W1967501399 @default.
- W1782652550 cites W1987926731 @default.
- W1782652550 cites W2018534020 @default.
- W1782652550 cites W2057570168 @default.
- W1782652550 cites W2062804922 @default.
- W1782652550 cites W2074424087 @default.
- W1782652550 cites W2075612789 @default.
- W1782652550 cites W2091764247 @default.
- W1782652550 cites W2184206420 @default.
- W1782652550 cites W2409297289 @default.
- W1782652550 cites W2409516269 @default.
- W1782652550 cites W2419660946 @default.
- W1782652550 cites W2444554292 @default.
- W1782652550 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9669393" @default.
- W1782652550 hasPublicationYear "1998" @default.
- W1782652550 type Work @default.
- W1782652550 sameAs 1782652550 @default.
- W1782652550 citedByCount "26" @default.
- W1782652550 countsByYear W17826525502012 @default.
- W1782652550 countsByYear W17826525502013 @default.
- W1782652550 countsByYear W17826525502014 @default.
- W1782652550 countsByYear W17826525502016 @default.
- W1782652550 countsByYear W17826525502018 @default.
- W1782652550 crossrefType "journal-article" @default.
- W1782652550 hasAuthorship W1782652550A5008622761 @default.
- W1782652550 hasAuthorship W1782652550A5011887107 @default.
- W1782652550 hasAuthorship W1782652550A5046601855 @default.
- W1782652550 hasAuthorship W1782652550A5049419102 @default.
- W1782652550 hasAuthorship W1782652550A5066125769 @default.
- W1782652550 hasAuthorship W1782652550A5079389598 @default.
- W1782652550 hasAuthorship W1782652550A5087307905 @default.
- W1782652550 hasConcept C121608353 @default.
- W1782652550 hasConcept C126322002 @default.
- W1782652550 hasConcept C2776694085 @default.
- W1782652550 hasConcept C2777546739 @default.
- W1782652550 hasConcept C2779013556 @default.
- W1782652550 hasConcept C2780456651 @default.
- W1782652550 hasConcept C2989005 @default.
- W1782652550 hasConcept C526805850 @default.
- W1782652550 hasConcept C71924100 @default.
- W1782652550 hasConceptScore W1782652550C121608353 @default.
- W1782652550 hasConceptScore W1782652550C126322002 @default.
- W1782652550 hasConceptScore W1782652550C2776694085 @default.
- W1782652550 hasConceptScore W1782652550C2777546739 @default.
- W1782652550 hasConceptScore W1782652550C2779013556 @default.
- W1782652550 hasConceptScore W1782652550C2780456651 @default.
- W1782652550 hasConceptScore W1782652550C2989005 @default.
- W1782652550 hasConceptScore W1782652550C526805850 @default.
- W1782652550 hasConceptScore W1782652550C71924100 @default.
- W1782652550 hasIssue "7" @default.
- W1782652550 hasLocation W17826525501 @default.
- W1782652550 hasOpenAccess W1782652550 @default.
- W1782652550 hasPrimaryLocation W17826525501 @default.
- W1782652550 hasRelatedWork W160790845 @default.
- W1782652550 hasRelatedWork W1771671972 @default.
- W1782652550 hasRelatedWork W2003306235 @default.
- W1782652550 hasRelatedWork W2024537967 @default.
- W1782652550 hasRelatedWork W2066883220 @default.
- W1782652550 hasRelatedWork W2098292062 @default.
- W1782652550 hasRelatedWork W2384895649 @default.
- W1782652550 hasRelatedWork W2419399195 @default.
- W1782652550 hasRelatedWork W2425780956 @default.
- W1782652550 hasRelatedWork W2972697340 @default.
- W1782652550 hasVolume "39" @default.
- W1782652550 isParatext "false" @default.
- W1782652550 isRetracted "false" @default.
- W1782652550 magId "1782652550" @default.
- W1782652550 workType "article" @default.