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• W1783468416 abstract "textabstractOsteoporosis is characterized by low bone mass and microarchitectural deterioration ofbone tissue, leading to enhanced bone fragility and a consequent increase in fracturerisk. Osteoporosis is a major public health problem involving postmenopausal womenand aging individuals. The lifetime risk of osteoporotic fractures of the vertebralbodies (symptomatic), hip, and distal radius is about 40 % for white women and 13 %for white men. At present, the best possibility to assess the fracture risk of anindividual is the measurement of bone mass (g) or bone mineral density (BMD, glcm).Studies in postmenopausal women showed that for each standard deviation decrease inBMD there was a 2-3 fold increase in fracture risk. Bone mass later in life isdetermined by the peak bone mass acquired during adolescence and the subsequent rateof bone loss. Low peak bone mass results in a higher risk of osteoporosis. A highpeak bone mass provides a larger reserve later in life.BMD increases during childhood until the peak bone mass is achieved, around the ageof 18 to 20 years. Thereafter, bone mass stabilizes and then decreases progressivelyin both sexes after 35 to 40 years of age with a steeper decline in women after themenopause." @default.
• W1783468416 created "2016-06-24" @default.
• W1783468416 creator A5000420191 @default.
• W1783468416 date "1997-10-08" @default.
• W1783468416 modified "2023-09-24" @default.
• W1783468416 title "Bone mineral density and body composition of children and adolescents in health and disease" @default.
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