Matches in SemOpenAlex for { <https://semopenalex.org/work/W1783949284> ?p ?o ?g. }
- W1783949284 endingPage "295" @default.
- W1783949284 startingPage "289" @default.
- W1783949284 abstract "Abstract Early neonatal handling of rat pups produces dampened hypothalamic‐pituitary‐adrenal axis reactivity to stress in adult male offspring. However, less is known about whether there is a similar effect for females. Although, most studies of neonatal handling have examined subsequent effects during adulthood, adolescence is an important developmental stage for stress responsivity. To address these issues, the effect of neonatal handling on the endocrine stress response and brain activity of male and female rats was determined in response to acute restraint stress during adolescence. Consistent with previous findings in adult males, neonatal handling reduced restraint stress‐induced hormone levels in adolescent males. However, in contrast, we found elevated plasma hormone concentrations in handled females. A gender‐specific handling effect on brain activity was also evident, with significantly increased stress‐induced activation of the posterior cingulate cortex of handled females, as measured by c‐ fos mRNA expression. The striking gender difference in the effect of early neonatal handling provides evidence that this must be considered as an important variable in subsequent stress responsivity induced by early manipulations." @default.
- W1783949284 created "2016-06-24" @default.
- W1783949284 creator A5042013474 @default.
- W1783949284 creator A5067988513 @default.
- W1783949284 creator A5088026484 @default.
- W1783949284 creator A5091211255 @default.
- W1783949284 date "2003-02-13" @default.
- W1783949284 modified "2023-10-15" @default.
- W1783949284 title "Gender Specific Effect of Neonatal Handling on Stress Reactivity of Adolescent Rats" @default.
- W1783949284 cites W105884881 @default.
- W1783949284 cites W1514751206 @default.
- W1783949284 cites W1532805410 @default.
- W1783949284 cites W1541716248 @default.
- W1783949284 cites W1920051840 @default.
- W1783949284 cites W1965788374 @default.
- W1783949284 cites W1966224650 @default.
- W1783949284 cites W1973227963 @default.
- W1783949284 cites W1973518997 @default.
- W1783949284 cites W1980057501 @default.
- W1783949284 cites W1981021369 @default.
- W1783949284 cites W1981149106 @default.
- W1783949284 cites W1983633003 @default.
- W1783949284 cites W1984427714 @default.
- W1783949284 cites W1985543379 @default.
- W1783949284 cites W1985645068 @default.
- W1783949284 cites W1985669446 @default.
- W1783949284 cites W2003656057 @default.
- W1783949284 cites W2007005063 @default.
- W1783949284 cites W2014570372 @default.
- W1783949284 cites W2015957938 @default.
- W1783949284 cites W2017034268 @default.
- W1783949284 cites W2017690535 @default.
- W1783949284 cites W2024978066 @default.
- W1783949284 cites W2025372892 @default.
- W1783949284 cites W2029323039 @default.
- W1783949284 cites W2031183921 @default.
- W1783949284 cites W2034476672 @default.
- W1783949284 cites W2036587591 @default.
- W1783949284 cites W2039583040 @default.
- W1783949284 cites W2041286758 @default.
- W1783949284 cites W2044154535 @default.
- W1783949284 cites W2047908047 @default.
- W1783949284 cites W2049931904 @default.
- W1783949284 cites W2054220422 @default.
- W1783949284 cites W2054229769 @default.
- W1783949284 cites W2054692302 @default.
- W1783949284 cites W2055161357 @default.
- W1783949284 cites W2056280621 @default.
- W1783949284 cites W2061200619 @default.
- W1783949284 cites W2073047972 @default.
- W1783949284 cites W2079745118 @default.
- W1783949284 cites W2080308136 @default.
- W1783949284 cites W2089160338 @default.
- W1783949284 cites W2091497325 @default.
- W1783949284 cites W2091655849 @default.
- W1783949284 cites W2091987951 @default.
- W1783949284 cites W2104463303 @default.
- W1783949284 cites W2120743339 @default.
- W1783949284 cites W2127504265 @default.
- W1783949284 cites W2149915148 @default.
- W1783949284 cites W2155218627 @default.
- W1783949284 cites W2162045610 @default.
- W1783949284 cites W2171584675 @default.
- W1783949284 cites W2329876235 @default.
- W1783949284 cites W2416984069 @default.
- W1783949284 cites W4232546639 @default.
- W1783949284 cites W4249341192 @default.
- W1783949284 doi "https://doi.org/10.1046/j.1365-2826.2003.01010.x" @default.
- W1783949284 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12588518" @default.
- W1783949284 hasPublicationYear "2003" @default.
- W1783949284 type Work @default.
- W1783949284 sameAs 1783949284 @default.
- W1783949284 citedByCount "61" @default.
- W1783949284 countsByYear W17839492842012 @default.
- W1783949284 countsByYear W17839492842013 @default.
- W1783949284 countsByYear W17839492842014 @default.
- W1783949284 countsByYear W17839492842015 @default.
- W1783949284 countsByYear W17839492842016 @default.
- W1783949284 countsByYear W17839492842017 @default.
- W1783949284 countsByYear W17839492842018 @default.
- W1783949284 countsByYear W17839492842019 @default.
- W1783949284 countsByYear W17839492842021 @default.
- W1783949284 crossrefType "journal-article" @default.
- W1783949284 hasAuthorship W1783949284A5042013474 @default.
- W1783949284 hasAuthorship W1783949284A5067988513 @default.
- W1783949284 hasAuthorship W1783949284A5088026484 @default.
- W1783949284 hasAuthorship W1783949284A5091211255 @default.
- W1783949284 hasConcept C112672928 @default.
- W1783949284 hasConcept C126322002 @default.
- W1783949284 hasConcept C134018914 @default.
- W1783949284 hasConcept C15744967 @default.
- W1783949284 hasConcept C2776443723 @default.
- W1783949284 hasConcept C2778945730 @default.
- W1783949284 hasConcept C2779234561 @default.
- W1783949284 hasConcept C2780352252 @default.
- W1783949284 hasConcept C46699223 @default.
- W1783949284 hasConcept C54355233 @default.
- W1783949284 hasConcept C71315377 @default.