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- W1784204876 abstract "Abstract The mouse macrophage (MΦ) cell line IC-21 preferentially ingests a subpopulation of homologous red blood cells (MRBC) from normal mice. This subpopulation presumably bears the so-called transfusion lesion, a consequence of damage acquired during the drawing and processing of blood. To determine if all damaged MRBC were recognized by a common receptor site on IC-21 MΦ, we prepared suspensions of MRBC damaged in vitro by treatment with tannic acid and compared the phagocytic uptake of these cells with those bearing the transfusion lesion. Trypsin treatment of IC-21 MΦ rendered them unable to recognize MRBC bearing the transfusion lesion; but it had no effect on the uptake of tannic acid-damaged MRBC, showing that IC-21 MΦ have separate recognition sites for these two populations of damaged MRBC." @default.
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- W1784204876 date "1987-06-01" @default.
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- W1784204876 title "Red Blood Cell Homeostasis: Recognition of Distinct Types of Damaged Homologous Red Blood Cells by a Mouse Macrophage Cell Line" @default.
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- W1784204876 doi "https://doi.org/10.1002/jlb.41.6.500" @default.
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