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- W178441652 abstract "Human endothelial cells have been found to be relatively refractory to various methods of DNA transfection currently in common use. By using a transfection method involving DNA complexed with replication-deficient adenovirus particles, we have shown that 20% of a population of cultured endothelial cells can be transfected and high levels of transient expression achieved. Both early-passage human umbilical vein endothelial cells and the continuous differentiated line of human endothelium-derived EA.hy926 cells are responsive to this method of transfection. Efficient DNA transfection of endothelial cells is important for studies of endothelium-specific promoters and is a potentially useful route for transgenic therapy." @default.
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- W178441652 date "1998-08-01" @default.
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- W178441652 title "Efficient Gene Transfer to Human Endothelial Cells Using DNA Complexed to Adenovirus Particles" @default.
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- W178441652 doi "https://doi.org/10.2144/98252gt01" @default.
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