FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1784856208> ?p ?o ?g. }

• W1784856208 endingPage "4343" @default.
• W1784856208 startingPage "4335" @default.
• W1784856208 abstract "Conduction block is a mechanism of activity-dependent neuronal plasticity, but little is known about its possible neuromodulation. Extensive activity in leech touch (T), pressure (P), and nociceptive (N) mechanosensory neurons results in conduction block of their minor receptive fields. We have examined whether the duration of conduction block could be modulated by the serotonergic Retzius neurons or by application of serotonin (5-HT). Activation of one Retzius cell reduced the duration of conduction block in T and P cell posterior fields, but their anterior fields and N cell fields were unaffected. Perfusion with 5-HT had stronger effects, reducing the duration of conduction block in T, P, and lateral N cells in the posterior fields and either reducing or more often enhancing the expression of conduction block in anterior fields. The effects of 5-HT on posterior fields were blocked by the nonspecific 5-HT antagonist methysergide and were partly suppressed by the 5-HT 2 antagonist ketanserin. To determine the site of 5-HT action, the central ganglion or peripheral skin was perfused independently. T and to a greater extent P cells showed a preferential sensitivity to application of 5-HT onto the central ganglion. Interestingly, medial N cells exhibited a progressive decrease in the duration of conduction block during repeated trials (“wind-up”) that was unaffected by 5-HT. We conclude that secretion of 5-HT by the Retzius cells has a central modulatory effect on the duration of conduction block in T, P, and lateral N cells." @default.
• W1784856208 created "2016-06-24" @default.
• W1784856208 creator A5022062828 @default.
• W1784856208 creator A5061437247 @default.
• W1784856208 date "1996-07-15" @default.
• W1784856208 modified "2023-10-15" @default.
• W1784856208 title "Modulation of Conduction Block in Leech Mechanosensory Neurons" @default.
• W1784856208 cites W1853572663 @default.
• W1784856208 cites W1872585649 @default.
• W1784856208 cites W1902428143 @default.
• W1784856208 cites W1932094717 @default.
• W1784856208 cites W1950855598 @default.
• W1784856208 cites W1973406013 @default.
• W1784856208 cites W1982317081 @default.
• W1784856208 cites W1985024007 @default.
• W1784856208 cites W1988059170 @default.
• W1784856208 cites W1988354120 @default.
• W1784856208 cites W1998308407 @default.
• W1784856208 cites W1999668334 @default.
• W1784856208 cites W2007946757 @default.
• W1784856208 cites W2008998885 @default.
• W1784856208 cites W2013696064 @default.
• W1784856208 cites W2024417066 @default.
• W1784856208 cites W2038170923 @default.
• W1784856208 cites W2046317880 @default.
• W1784856208 cites W2048035298 @default.
• W1784856208 cites W2055568369 @default.
• W1784856208 cites W2063957486 @default.
• W1784856208 cites W2063978774 @default.
• W1784856208 cites W2065245499 @default.
• W1784856208 cites W2067065070 @default.
• W1784856208 cites W2081599487 @default.
• W1784856208 cites W2081611679 @default.
• W1784856208 cites W2086729362 @default.
• W1784856208 cites W2091288137 @default.
• W1784856208 cites W2093474353 @default.
• W1784856208 cites W2132224384 @default.
• W1784856208 cites W2137836504 @default.
• W1784856208 cites W2158248534 @default.
• W1784856208 cites W2159460364 @default.
• W1784856208 cites W2260534654 @default.
• W1784856208 cites W2266324655 @default.
• W1784856208 cites W2270283363 @default.
• W1784856208 cites W2395908351 @default.
• W1784856208 cites W2403786428 @default.
• W1784856208 cites W2410708907 @default.
• W1784856208 cites W2413002250 @default.
• W1784856208 cites W2414723798 @default.
• W1784856208 cites W2415369909 @default.
• W1784856208 cites W2415567272 @default.
• W1784856208 cites W2460995592 @default.
• W1784856208 cites W2754205450 @default.
• W1784856208 doi "https://doi.org/10.1523/jneurosci.16-14-04335.1996" @default.
• W1784856208 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6578854" @default.
• W1784856208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8699244" @default.
• W1784856208 hasPublicationYear "1996" @default.
• W1784856208 type Work @default.
• W1784856208 sameAs 1784856208 @default.
• W1784856208 citedByCount "49" @default.
• W1784856208 countsByYear W17848562082012 @default.
• W1784856208 countsByYear W17848562082015 @default.
• W1784856208 countsByYear W17848562082019 @default.
• W1784856208 countsByYear W17848562082020 @default.
• W1784856208 countsByYear W17848562082021 @default.
• W1784856208 countsByYear W17848562082022 @default.
• W1784856208 countsByYear W17848562082023 @default.
• W1784856208 crossrefType "journal-article" @default.
• W1784856208 hasAuthorship W1784856208A5022062828 @default.
• W1784856208 hasAuthorship W1784856208A5061437247 @default.
• W1784856208 hasBestOaLocation W17848562081 @default.
• W1784856208 hasConcept C105702510 @default.
• W1784856208 hasConcept C12554922 @default.
• W1784856208 hasConcept C126322002 @default.
• W1784856208 hasConcept C136764020 @default.
• W1784856208 hasConcept C169760540 @default.
• W1784856208 hasConcept C170493617 @default.
• W1784856208 hasConcept C180746962 @default.
• W1784856208 hasConcept C185263204 @default.
• W1784856208 hasConcept C185592680 @default.
• W1784856208 hasConcept C19071747 @default.
• W1784856208 hasConcept C2775864247 @default.
• W1784856208 hasConcept C2777785214 @default.
• W1784856208 hasConcept C2781005078 @default.
• W1784856208 hasConcept C37000724 @default.
• W1784856208 hasConcept C41008148 @default.
• W1784856208 hasConcept C53910766 @default.
• W1784856208 hasConcept C71924100 @default.
• W1784856208 hasConcept C86803240 @default.
• W1784856208 hasConceptScore W1784856208C105702510 @default.
• W1784856208 hasConceptScore W1784856208C12554922 @default.
• W1784856208 hasConceptScore W1784856208C126322002 @default.
• W1784856208 hasConceptScore W1784856208C136764020 @default.
• W1784856208 hasConceptScore W1784856208C169760540 @default.
• W1784856208 hasConceptScore W1784856208C170493617 @default.
• W1784856208 hasConceptScore W1784856208C180746962 @default.
• W1784856208 hasConceptScore W1784856208C185263204 @default.
• W1784856208 hasConceptScore W1784856208C185592680 @default.
• W1784856208 hasConceptScore W1784856208C19071747 @default.

• next