FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1785227132> ?p ?o ?g. }

• W1785227132 endingPage "1690" @default.
• W1785227132 startingPage "1685" @default.
• W1785227132 abstract "The effect of age on telomere length heterogeneity in men has not been studied previously. Our aims were to determine the relationship between variation in sperm telomere length (STL), men's age, and semen parameters in spermatozoa from men undergoing in vitro fertilization (IVF) treatment.To perform this prospective cross-sectional pilot study, telomere length was estimated in 200 individual spermatozoa from men undergoing IVF treatment at the NYU Fertility Center. A novel single-cell telomere content assay (SCT-pqPCR) measured telomere length in individual spermatozoa.Telomere length among individual spermatozoa within an ejaculate varies markedly and increases with age. Older men not only have longer STL but also have more variable STL compared to younger men. STL from samples with normal semen parameters was significantly longer than that from samples with abnormal parameters, but STL did not differ between spermatozoa with normal versus abnormal morphology.The marked increase in STL heterogeneity as men age is consistent with a role for ALT during spermatogenesis. No data have yet reported the effect of age on STL heterogeneity. Based on these results, future studies should expand this modest sample size to search for molecular evidence of ALT in human testes during spermatogenesis." @default.
• W1785227132 created "2016-06-24" @default.
• W1785227132 creator A5002661071 @default.
• W1785227132 creator A5003024333 @default.
• W1785227132 creator A5008024102 @default.
• W1785227132 creator A5014162026 @default.
• W1785227132 creator A5023456046 @default.
• W1785227132 creator A5050729443 @default.
• W1785227132 creator A5078033317 @default.
• W1785227132 creator A5086851877 @default.
• W1785227132 creator A5091228326 @default.
• W1785227132 date "2015-09-28" @default.
• W1785227132 modified "2023-09-27" @default.
• W1785227132 title "A single-cell assay for telomere DNA content shows increasing telomere length heterogeneity, as well as increasing mean telomere length in human spermatozoa with advancing age" @default.
• W1785227132 cites W1579661837 @default.
• W1785227132 cites W1600373583 @default.
• W1785227132 cites W1612842202 @default.
• W1785227132 cites W1920232451 @default.
• W1785227132 cites W1970414153 @default.
• W1785227132 cites W1971053085 @default.
• W1785227132 cites W1979794741 @default.
• W1785227132 cites W1991841515 @default.
• W1785227132 cites W1998663807 @default.
• W1785227132 cites W1998749128 @default.
• W1785227132 cites W1999104687 @default.
• W1785227132 cites W2025043712 @default.
• W1785227132 cites W2045951927 @default.
• W1785227132 cites W2047939916 @default.
• W1785227132 cites W2054592293 @default.
• W1785227132 cites W2060955969 @default.
• W1785227132 cites W2071484008 @default.
• W1785227132 cites W2071673220 @default.
• W1785227132 cites W2102111774 @default.
• W1785227132 cites W2106808509 @default.
• W1785227132 cites W2119463579 @default.
• W1785227132 cites W2124098526 @default.
• W1785227132 cites W2128708127 @default.
• W1785227132 cites W2136856258 @default.
• W1785227132 cites W2143332522 @default.
• W1785227132 cites W2144779297 @default.
• W1785227132 cites W2147336921 @default.
• W1785227132 cites W2152588928 @default.
• W1785227132 cites W2161948433 @default.
• W1785227132 cites W2163211502 @default.
• W1785227132 cites W2170528713 @default.
• W1785227132 cites W2231999257 @default.
• W1785227132 doi "https://doi.org/10.1007/s10815-015-0574-3" @default.
• W1785227132 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4651947" @default.
• W1785227132 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26411311" @default.
• W1785227132 hasPublicationYear "2015" @default.
• W1785227132 type Work @default.
• W1785227132 sameAs 1785227132 @default.
• W1785227132 citedByCount "41" @default.
• W1785227132 countsByYear W17852271322015 @default.
• W1785227132 countsByYear W17852271322016 @default.
• W1785227132 countsByYear W17852271322017 @default.
• W1785227132 countsByYear W17852271322018 @default.
• W1785227132 countsByYear W17852271322019 @default.
• W1785227132 countsByYear W17852271322020 @default.
• W1785227132 countsByYear W17852271322021 @default.
• W1785227132 countsByYear W17852271322022 @default.
• W1785227132 countsByYear W17852271322023 @default.
• W1785227132 crossrefType "journal-article" @default.
• W1785227132 hasAuthorship W1785227132A5002661071 @default.
• W1785227132 hasAuthorship W1785227132A5003024333 @default.
• W1785227132 hasAuthorship W1785227132A5008024102 @default.
• W1785227132 hasAuthorship W1785227132A5014162026 @default.
• W1785227132 hasAuthorship W1785227132A5023456046 @default.
• W1785227132 hasAuthorship W1785227132A5050729443 @default.
• W1785227132 hasAuthorship W1785227132A5078033317 @default.
• W1785227132 hasAuthorship W1785227132A5086851877 @default.
• W1785227132 hasAuthorship W1785227132A5091228326 @default.
• W1785227132 hasBestOaLocation W17852271322 @default.
• W1785227132 hasConcept C123765429 @default.
• W1785227132 hasConcept C16685009 @default.
• W1785227132 hasConcept C177336024 @default.
• W1785227132 hasConcept C2778093475 @default.
• W1785227132 hasConcept C2781087480 @default.
• W1785227132 hasConcept C54355233 @default.
• W1785227132 hasConcept C552990157 @default.
• W1785227132 hasConcept C71924100 @default.
• W1785227132 hasConcept C86803240 @default.
• W1785227132 hasConceptScore W1785227132C123765429 @default.
• W1785227132 hasConceptScore W1785227132C16685009 @default.
• W1785227132 hasConceptScore W1785227132C177336024 @default.
• W1785227132 hasConceptScore W1785227132C2778093475 @default.
• W1785227132 hasConceptScore W1785227132C2781087480 @default.
• W1785227132 hasConceptScore W1785227132C54355233 @default.
• W1785227132 hasConceptScore W1785227132C552990157 @default.
• W1785227132 hasConceptScore W1785227132C71924100 @default.
• W1785227132 hasConceptScore W1785227132C86803240 @default.
• W1785227132 hasIssue "11" @default.
• W1785227132 hasLocation W17852271321 @default.
• W1785227132 hasLocation W17852271322 @default.
• W1785227132 hasLocation W17852271323 @default.
• W1785227132 hasLocation W17852271324 @default.
• W1785227132 hasOpenAccess W1785227132 @default.
• W1785227132 hasPrimaryLocation W17852271321 @default.

• next