FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1787568382> ?p ?o ?g. }

• W1787568382 endingPage "14" @default.
• W1787568382 startingPage "1" @default.
• W1787568382 abstract "B-cell acute lymphoblastic leukemia (B-ALL) is a serious public health problem in the pediatric population worldwide, contributing to 85% of deaths from childhood cancers. Understanding the biology of the disease is crucial for its clinical management and the development of therapeutic strategies. In line with that observed in other malignancies, chronic inflammation may contribute to a tumor microenvironment resulting in the damage of normal processes, concomitant to development and maintenance of neoplastic cells. We report here that hematopoietic cells from bone marrow B-ALL have the ability to produce proinflammatory and growth factors, including TNFα, IL-1β, IL-12, and GM-CSF that stimulate proliferation and differentiation of normal stem and progenitor cells. Our findings suggest an apparently distinct CD13(+)CD33(+) population of leukemic cells contributing to a proinflammatory microenvironment that may be detrimental to long-term normal hematopoiesis within B-ALL bone marrow." @default.
• W1787568382 created "2016-06-24" @default.
• W1787568382 creator A5006349708 @default.
• W1787568382 creator A5012584373 @default.
• W1787568382 creator A5012778546 @default.
• W1787568382 creator A5032936893 @default.
• W1787568382 creator A5036655418 @default.
• W1787568382 creator A5054793563 @default.
• W1787568382 creator A5055123489 @default.
• W1787568382 creator A5055797678 @default.
• W1787568382 creator A5061022456 @default.
• W1787568382 creator A5064474448 @default.
• W1787568382 creator A5064631995 @default.
• W1787568382 date "2015-01-01" @default.
• W1787568382 modified "2023-10-18" @default.
• W1787568382 title "Bone Marrow Cells in Acute Lymphoblastic Leukemia Create a Proinflammatory Microenvironment Influencing Normal Hematopoietic Differentiation Fates" @default.
• W1787568382 cites W1533021978 @default.
• W1787568382 cites W1591847053 @default.
• W1787568382 cites W1603578230 @default.
• W1787568382 cites W1834969374 @default.
• W1787568382 cites W1918515708 @default.
• W1787568382 cites W1964110508 @default.
• W1787568382 cites W1973099013 @default.
• W1787568382 cites W1973234860 @default.
• W1787568382 cites W1973389174 @default.
• W1787568382 cites W1975826301 @default.
• W1787568382 cites W1977758974 @default.
• W1787568382 cites W1983617908 @default.
• W1787568382 cites W1988356885 @default.
• W1787568382 cites W2001233352 @default.
• W1787568382 cites W2002908678 @default.
• W1787568382 cites W2003538143 @default.
• W1787568382 cites W2004855073 @default.
• W1787568382 cites W2009093325 @default.
• W1787568382 cites W2017812982 @default.
• W1787568382 cites W2019145099 @default.
• W1787568382 cites W2020622102 @default.
• W1787568382 cites W2025193872 @default.
• W1787568382 cites W2026970599 @default.
• W1787568382 cites W2029914681 @default.
• W1787568382 cites W2034481786 @default.
• W1787568382 cites W2038802455 @default.
• W1787568382 cites W2041168245 @default.
• W1787568382 cites W2043034449 @default.
• W1787568382 cites W2046830231 @default.
• W1787568382 cites W2050628678 @default.
• W1787568382 cites W2051303553 @default.
• W1787568382 cites W2060672294 @default.
• W1787568382 cites W2063582323 @default.
• W1787568382 cites W2064672822 @default.
• W1787568382 cites W2064736350 @default.
• W1787568382 cites W2071048246 @default.
• W1787568382 cites W2072411272 @default.
• W1787568382 cites W2081107312 @default.
• W1787568382 cites W2082284294 @default.
• W1787568382 cites W2086969890 @default.
• W1787568382 cites W2091742850 @default.
• W1787568382 cites W2101526959 @default.
• W1787568382 cites W2103379368 @default.
• W1787568382 cites W2103456976 @default.
• W1787568382 cites W2104849855 @default.
• W1787568382 cites W2114236835 @default.
• W1787568382 cites W2119752261 @default.
• W1787568382 cites W2123105952 @default.
• W1787568382 cites W2123870112 @default.
• W1787568382 cites W2130085747 @default.
• W1787568382 cites W2143320043 @default.
• W1787568382 cites W2144737008 @default.
• W1787568382 cites W2169281418 @default.
• W1787568382 cites W2315613727 @default.
• W1787568382 cites W2470611875 @default.
• W1787568382 doi "https://doi.org/10.1155/2015/386165" @default.
• W1787568382 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4450234" @default.
• W1787568382 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26090405" @default.
• W1787568382 hasPublicationYear "2015" @default.
• W1787568382 type Work @default.
• W1787568382 sameAs 1787568382 @default.
• W1787568382 citedByCount "35" @default.
• W1787568382 countsByYear W17875683822015 @default.
• W1787568382 countsByYear W17875683822016 @default.
• W1787568382 countsByYear W17875683822017 @default.
• W1787568382 countsByYear W17875683822018 @default.
• W1787568382 countsByYear W17875683822019 @default.
• W1787568382 countsByYear W17875683822020 @default.
• W1787568382 countsByYear W17875683822021 @default.
• W1787568382 countsByYear W17875683822022 @default.
• W1787568382 countsByYear W17875683822023 @default.
• W1787568382 crossrefType "journal-article" @default.
• W1787568382 hasAuthorship W1787568382A5006349708 @default.
• W1787568382 hasAuthorship W1787568382A5012584373 @default.
• W1787568382 hasAuthorship W1787568382A5012778546 @default.
• W1787568382 hasAuthorship W1787568382A5032936893 @default.
• W1787568382 hasAuthorship W1787568382A5036655418 @default.
• W1787568382 hasAuthorship W1787568382A5054793563 @default.
• W1787568382 hasAuthorship W1787568382A5055123489 @default.
• W1787568382 hasAuthorship W1787568382A5055797678 @default.
• W1787568382 hasAuthorship W1787568382A5061022456 @default.
• W1787568382 hasAuthorship W1787568382A5064474448 @default.

• next