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- W178768505 abstract "In this prospective, randomized, controlled study, we evaluate the safety and change of left ventricular systolic function and infarct area with varied imaging techniques after BMCs transplantation in AMI patients within 3 h after emergency percutaneous coronary intervention (PCI). A total of 271 patients with a first ST-segment-elevation myocardial infarction who had undergone stenting of the infarct-related artery were randomly assigned to receive either unselected BMCs (n=137) transplant or saline (n=134) within 3 hours after successful PCI to the distal vessel of the infarct-related artery through micro-catheter. All patients were followed up within 12 months. Intracoronary BMCs application did not incur cardiovascular events, including ventricular arrhythmias or syncope, occurred during 12-month follow-up. By quantitative LV angiography at six months, LV ejection fraction (LVEF) significantly increased ( p <0.001) and the change of LVEF significantly higher than that in the control group ( p <0.001). Contrast-enhanced magnetic resonance imaging after one year revealed an increased EF (7.7%±6.9%), reduced infarct size (−7.0%±7.5%). In patients with AMI, intracoronary infusion of BMCs within 3 hours after primary PCI is effective and safe in long-term follow-up." @default.
- W178768505 created "2016-06-24" @default.
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- W178768505 date "2008-10-28" @default.
- W178768505 modified "2023-09-26" @default.
- W178768505 title "Abstract 2878: Emergency Intracoronary Stem Cell Transplantation in Patients with Acute Myocardial Infarction (TCT-STAMI-2): Long-Term Outcome" @default.
- W178768505 doi "https://doi.org/10.1161/circ.118.suppl_18.s_791" @default.
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