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- W1787741637 abstract "The 5' control region and first exon for human X-chromosome-linked phosphoglycerate kinase is contained in a G + C-rich island. We measured methylation at all HpaII sites in this 5' region of leukocyte DNA. By use of a blotting procedure that allows analysis of small DNA fragments, we found that the HpaII sites are entirely methylated when from an inactive X chromosome and entirely unmethylated when from an active one. In contrast, methylation of HpaII sites in more downstream regions of the gene is essentially the same in active and inactive X chromosomes." @default.
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- W1787741637 date "1986-11-01" @default.
- W1787741637 modified "2023-09-26" @default.
- W1787741637 title "Active X chromosome DNA is unmethylated at eight CCGG sites clustered in a guanine-plus-cytosine-rich island at the 5' end of the gene for phosphoglycerate kinase." @default.
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- W1787741637 doi "https://doi.org/10.1128/mcb.6.11.4122" @default.
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