FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1787847872> ?p ?o ?g. }

• W1787847872 endingPage "1705" @default.
• W1787847872 startingPage "1698" @default.
• W1787847872 abstract "Kinetic hydrate inhibitors (KHIs) are used commercially to inhibit gas hydrate formation and growth in pipelines. However, improvement of these polymers has been constrained by the lack of verified molecular models. Since antifreeze proteins (AFPs) act as KHIs, we have used their solved x-ray crystallographic structures in molecular modeling to explore gas hydrate inhibition. The internal clathrate water network of the fish AFP Maxi, which extends to the protein’s outer surface, is remarkably similar to the {100} planes of structure type II (sII) gas hydrate. The crystal structure of this water web has facilitated the construction of in silico models for Maxi and type I AFP binding to sII hydrates. Here, we have substantiated our models with experimental evidence of Maxi binding to the tetrahydrofuran sII model hydrate. Both in silico and experimental evidence support the absorbance-inhibition mechanism proposed for KHI binding to gas hydrates. Based on the Maxi crystal structure we suggest that the inhibitor adsorbs to the gas hydrate lattice through the same anchored clathrate water mechanism used to bind ice. These results will facilitate the rational design of a next generation of effective green KHIs for the petroleum industry to ensure safe and efficient hydrocarbon flow." @default.
• W1787847872 created "2016-06-24" @default.
• W1787847872 creator A5017390574 @default.
• W1787847872 creator A5035023245 @default.
• W1787847872 creator A5089592588 @default.
• W1787847872 date "2015-10-01" @default.
• W1787847872 modified "2023-10-12" @default.
• W1787847872 title "Structural Basis for the Inhibition of Gas Hydrates by α -Helical Antifreeze Proteins" @default.
• W1787847872 cites W1483934113 @default.
• W1787847872 cites W1968936136 @default.
• W1787847872 cites W1972391295 @default.
• W1787847872 cites W1973787521 @default.
• W1787847872 cites W2003542069 @default.
• W1787847872 cites W2004765394 @default.
• W1787847872 cites W2007461858 @default.
• W1787847872 cites W2014295681 @default.
• W1787847872 cites W2027789621 @default.
• W1787847872 cites W2027910403 @default.
• W1787847872 cites W2030617384 @default.
• W1787847872 cites W2033472269 @default.
• W1787847872 cites W2037024981 @default.
• W1787847872 cites W2047640421 @default.
• W1787847872 cites W2052735760 @default.
• W1787847872 cites W2057373678 @default.
• W1787847872 cites W2074132624 @default.
• W1787847872 cites W2081125207 @default.
• W1787847872 cites W2082568744 @default.
• W1787847872 cites W2083397422 @default.
• W1787847872 cites W2084998672 @default.
• W1787847872 cites W2087968683 @default.
• W1787847872 cites W2088849221 @default.
• W1787847872 cites W2090026561 @default.
• W1787847872 cites W2090407041 @default.
• W1787847872 cites W2109532360 @default.
• W1787847872 cites W2117957872 @default.
• W1787847872 cites W2122895208 @default.
• W1787847872 cites W2131533270 @default.
• W1787847872 cites W2136450239 @default.
• W1787847872 cites W2142714761 @default.
• W1787847872 cites W2159382632 @default.
• W1787847872 cites W2167382751 @default.
• W1787847872 cites W2171268876 @default.
• W1787847872 cites W2324082424 @default.
• W1787847872 cites W2335293179 @default.
• W1787847872 doi "https://doi.org/10.1016/j.bpj.2015.08.041" @default.
• W1787847872 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4624156" @default.
• W1787847872 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26488661" @default.
• W1787847872 hasPublicationYear "2015" @default.
• W1787847872 type Work @default.
• W1787847872 sameAs 1787847872 @default.
• W1787847872 citedByCount "39" @default.
• W1787847872 countsByYear W17878478722016 @default.
• W1787847872 countsByYear W17878478722017 @default.
• W1787847872 countsByYear W17878478722018 @default.
• W1787847872 countsByYear W17878478722019 @default.
• W1787847872 countsByYear W17878478722020 @default.
• W1787847872 countsByYear W17878478722021 @default.
• W1787847872 countsByYear W17878478722022 @default.
• W1787847872 countsByYear W17878478722023 @default.
• W1787847872 crossrefType "journal-article" @default.
• W1787847872 hasAuthorship W1787847872A5017390574 @default.
• W1787847872 hasAuthorship W1787847872A5035023245 @default.
• W1787847872 hasAuthorship W1787847872A5089592588 @default.
• W1787847872 hasBestOaLocation W17878478721 @default.
• W1787847872 hasConcept C100402318 @default.
• W1787847872 hasConcept C104317684 @default.
• W1787847872 hasConcept C115624301 @default.
• W1787847872 hasConcept C141734981 @default.
• W1787847872 hasConcept C147597530 @default.
• W1787847872 hasConcept C178790620 @default.
• W1787847872 hasConcept C185592680 @default.
• W1787847872 hasConcept C2775905019 @default.
• W1787847872 hasConcept C2776170207 @default.
• W1787847872 hasConcept C2776701986 @default.
• W1787847872 hasConcept C2780471494 @default.
• W1787847872 hasConcept C2781060337 @default.
• W1787847872 hasConcept C55493867 @default.
• W1787847872 hasConcept C59593255 @default.
• W1787847872 hasConcept C71240020 @default.
• W1787847872 hasConcept C8010536 @default.
• W1787847872 hasConceptScore W1787847872C100402318 @default.
• W1787847872 hasConceptScore W1787847872C104317684 @default.
• W1787847872 hasConceptScore W1787847872C115624301 @default.
• W1787847872 hasConceptScore W1787847872C141734981 @default.
• W1787847872 hasConceptScore W1787847872C147597530 @default.
• W1787847872 hasConceptScore W1787847872C178790620 @default.
• W1787847872 hasConceptScore W1787847872C185592680 @default.
• W1787847872 hasConceptScore W1787847872C2775905019 @default.
• W1787847872 hasConceptScore W1787847872C2776170207 @default.
• W1787847872 hasConceptScore W1787847872C2776701986 @default.
• W1787847872 hasConceptScore W1787847872C2780471494 @default.
• W1787847872 hasConceptScore W1787847872C2781060337 @default.
• W1787847872 hasConceptScore W1787847872C55493867 @default.
• W1787847872 hasConceptScore W1787847872C59593255 @default.
• W1787847872 hasConceptScore W1787847872C71240020 @default.
• W1787847872 hasConceptScore W1787847872C8010536 @default.
• W1787847872 hasIssue "8" @default.
• W1787847872 hasLocation W17878478721 @default.

• next