FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1788046619> ?p ?o ?g. }

• W1788046619 endingPage "237" @default.
• W1788046619 startingPage "231" @default.
• W1788046619 abstract "Summary B cell activating factor (BAFF) plays a crucial role in the process of development, maturation and activation of B lymphocytes. Chronic hepatitis C virus (HCV) infection is characterized by multiple B cell disorders. It is a major cause of type II mixed cryoglobulinaemia (MC). We measured serum BAFF levels in several clinical situations to elucidate the potential role of BAFF in chronic HCV infection. We used a commercially available solid phase enzyme-linked immunosorbent assay. We estimated serum BAFF in stored sera from uninfected controls (n = 8), patients with chronic hepatitis B virus infection HBV (n = 5) and chronic HCV infection with (n = 16) and without mixed cryoglobulinaemia (n = 14). In two patients with HCV and MC we correlated BAFF with HCV RNA after pegylated interferon (peg-I). We correlated serum BAFF levels at baseline and at 12 weeks with treatment response: sustained virological response SVR (n = 5), non-responders (n = 6) and relapsers (n = 2). Finally, we estimated BAFF levels after complete depletion of B cells with rituximab in patients with chronic HCV with MC (n = 3). Serum levels of BAFF were increased in chronic HCV with MC, but not in chronic HBV infection, suggesting an association between BAFF and cryoglobulinaemia. Peg-I increased BAFF levels in serum and this paralleled HCV RNA very closely. Serum BAFF levels at week 12 of therapy with peg-I and R were significantly higher in responders than non-responders. Finally, B cell depletion was associated with markedly increased levels of BAFF." @default.
• W1788046619 created "2016-06-24" @default.
• W1788046619 creator A5031903911 @default.
• W1788046619 creator A5073144925 @default.
• W1788046619 creator A5083952064 @default.
• W1788046619 date "2012-10-05" @default.
• W1788046619 modified "2023-09-23" @default.
• W1788046619 title "B cell activating factor (BAFF) in the natural history of chronic hepatitis C virus liver disease and mixed cryoglobulinaemia" @default.
• W1788046619 cites W1485809788 @default.
• W1788046619 cites W1576993812 @default.
• W1788046619 cites W1596190107 @default.
• W1788046619 cites W1967082105 @default.
• W1788046619 cites W1978302597 @default.
• W1788046619 cites W1985300125 @default.
• W1788046619 cites W1991592276 @default.
• W1788046619 cites W1995025510 @default.
• W1788046619 cites W1999487724 @default.
• W1788046619 cites W2017046893 @default.
• W1788046619 cites W2019985783 @default.
• W1788046619 cites W2022841020 @default.
• W1788046619 cites W2024227112 @default.
• W1788046619 cites W2026549243 @default.
• W1788046619 cites W2027401883 @default.
• W1788046619 cites W2027545702 @default.
• W1788046619 cites W2032253670 @default.
• W1788046619 cites W2035868344 @default.
• W1788046619 cites W2043519223 @default.
• W1788046619 cites W2053375740 @default.
• W1788046619 cites W2054518275 @default.
• W1788046619 cites W2055338105 @default.
• W1788046619 cites W2056887208 @default.
• W1788046619 cites W2058912003 @default.
• W1788046619 cites W2061519346 @default.
• W1788046619 cites W2063431461 @default.
• W1788046619 cites W2077515082 @default.
• W1788046619 cites W2080657917 @default.
• W1788046619 cites W2090887217 @default.
• W1788046619 cites W2091850111 @default.
• W1788046619 cites W2114904233 @default.
• W1788046619 cites W2115603698 @default.
• W1788046619 cites W2134203563 @default.
• W1788046619 cites W2139167713 @default.
• W1788046619 cites W2139347834 @default.
• W1788046619 cites W2149476043 @default.
• W1788046619 cites W2171113939 @default.
• W1788046619 cites W2324507396 @default.
• W1788046619 doi "https://doi.org/10.1111/j.1365-2249.2012.04653.x" @default.
• W1788046619 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3482370" @default.
• W1788046619 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23039894" @default.
• W1788046619 hasPublicationYear "2012" @default.
• W1788046619 type Work @default.
• W1788046619 sameAs 1788046619 @default.
• W1788046619 citedByCount "22" @default.
• W1788046619 countsByYear W17880466192013 @default.
• W1788046619 countsByYear W17880466192014 @default.
• W1788046619 countsByYear W17880466192017 @default.
• W1788046619 countsByYear W17880466192018 @default.
• W1788046619 countsByYear W17880466192019 @default.
• W1788046619 countsByYear W17880466192020 @default.
• W1788046619 countsByYear W17880466192021 @default.
• W1788046619 countsByYear W17880466192022 @default.
• W1788046619 countsByYear W17880466192023 @default.
• W1788046619 crossrefType "journal-article" @default.
• W1788046619 hasAuthorship W1788046619A5031903911 @default.
• W1788046619 hasAuthorship W1788046619A5073144925 @default.
• W1788046619 hasAuthorship W1788046619A5083952064 @default.
• W1788046619 hasBestOaLocation W17880466192 @default.
• W1788046619 hasConcept C159047783 @default.
• W1788046619 hasConcept C159654299 @default.
• W1788046619 hasConcept C170286685 @default.
• W1788046619 hasConcept C203014093 @default.
• W1788046619 hasConcept C2522874641 @default.
• W1788046619 hasConcept C2776408679 @default.
• W1788046619 hasConcept C2776455275 @default.
• W1788046619 hasConcept C2778453870 @default.
• W1788046619 hasConcept C2780653079 @default.
• W1788046619 hasConcept C71924100 @default.
• W1788046619 hasConceptScore W1788046619C159047783 @default.
• W1788046619 hasConceptScore W1788046619C159654299 @default.
• W1788046619 hasConceptScore W1788046619C170286685 @default.
• W1788046619 hasConceptScore W1788046619C203014093 @default.
• W1788046619 hasConceptScore W1788046619C2522874641 @default.
• W1788046619 hasConceptScore W1788046619C2776408679 @default.
• W1788046619 hasConceptScore W1788046619C2776455275 @default.
• W1788046619 hasConceptScore W1788046619C2778453870 @default.
• W1788046619 hasConceptScore W1788046619C2780653079 @default.
• W1788046619 hasConceptScore W1788046619C71924100 @default.
• W1788046619 hasIssue "2" @default.
• W1788046619 hasLocation W17880466191 @default.
• W1788046619 hasLocation W17880466192 @default.
• W1788046619 hasLocation W17880466193 @default.
• W1788046619 hasOpenAccess W1788046619 @default.
• W1788046619 hasPrimaryLocation W17880466191 @default.
• W1788046619 hasRelatedWork W1505139021 @default.
• W1788046619 hasRelatedWork W2010282370 @default.
• W1788046619 hasRelatedWork W2045903301 @default.
• W1788046619 hasRelatedWork W2054615421 @default.
• W1788046619 hasRelatedWork W2061389251 @default.

• next