FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1788116981> ?p ?o ?g. }

• W1788116981 endingPage "230" @default.
• W1788116981 startingPage "221" @default.
• W1788116981 abstract "The objectives of this study were to develop a predictive statistical model for low-fill-weight capsule filling of inhalation products with dosator nozzles via the quality by design (QbD) approach and based on that to create refined models that include quadratic terms for significant parameters. Various controllable process parameters and uncontrolled material attributes of 12 powders were initially screened using a linear model with partial least square (PLS) regression to determine their effect on the critical quality attributes (CQA; fill weight and weight variability). After identifying critical material attributes (CMAs) and critical process parameters (CPPs) that influenced the CQA, model refinement was performed to study if interactions or quadratic terms influence the model. Based on the assessment of the effects of the CPPs and CMAs on fill weight and weight variability for low-fill-weight inhalation products, we developed an excellent linear predictive model for fill weight (R(2 )= 0.96, Q(2 )= 0.96 for powders with good flow properties and R(2 )= 0.94, Q(2 )= 0.93 for cohesive powders) and a model that provides a good approximation of the fill weight variability for each powder group. We validated the model, established a design space for the performance of different types of inhalation grade lactose on low-fill weight capsule filling and successfully used the CMAs and CPPs to predict fill weight of powders that were not included in the development set." @default.
• W1788116981 created "2016-06-24" @default.
• W1788116981 creator A5017620070 @default.
• W1788116981 creator A5023848615 @default.
• W1788116981 creator A5032152919 @default.
• W1788116981 creator A5036109780 @default.
• W1788116981 creator A5037916347 @default.
• W1788116981 creator A5040003588 @default.
• W1788116981 creator A5075876661 @default.
• W1788116981 creator A5090360163 @default.
• W1788116981 date "2015-05-29" @default.
• W1788116981 modified "2023-10-10" @default.
• W1788116981 title "Development of a design space and predictive statistical model for capsule filling of low-fill-weight inhalation products" @default.
• W1788116981 cites W1964209583 @default.
• W1788116981 cites W1981864971 @default.
• W1788116981 cites W1985405389 @default.
• W1788116981 cites W1988484664 @default.
• W1788116981 cites W1988857203 @default.
• W1788116981 cites W1989622438 @default.
• W1788116981 cites W1989801492 @default.
• W1788116981 cites W1991618236 @default.
• W1788116981 cites W1991847831 @default.
• W1788116981 cites W1992547859 @default.
• W1788116981 cites W1995125349 @default.
• W1788116981 cites W1997187492 @default.
• W1788116981 cites W1998831351 @default.
• W1788116981 cites W1999481657 @default.
• W1788116981 cites W2003091501 @default.
• W1788116981 cites W2010952801 @default.
• W1788116981 cites W2014039390 @default.
• W1788116981 cites W2015067714 @default.
• W1788116981 cites W2023950117 @default.
• W1788116981 cites W2024734747 @default.
• W1788116981 cites W2033509028 @default.
• W1788116981 cites W2039109129 @default.
• W1788116981 cites W2047356589 @default.
• W1788116981 cites W2073750282 @default.
• W1788116981 cites W2078430129 @default.
• W1788116981 cites W2088376206 @default.
• W1788116981 cites W2088581469 @default.
• W1788116981 cites W2129095933 @default.
• W1788116981 cites W2135471496 @default.
• W1788116981 cites W2158593151 @default.
• W1788116981 cites W2163882989 @default.
• W1788116981 cites W2167826073 @default.
• W1788116981 doi "https://doi.org/10.3109/03639045.2015.1040416" @default.
• W1788116981 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26023991" @default.
• W1788116981 hasPublicationYear "2015" @default.
• W1788116981 type Work @default.
• W1788116981 sameAs 1788116981 @default.
• W1788116981 citedByCount "10" @default.
• W1788116981 countsByYear W17881169812017 @default.
• W1788116981 countsByYear W17881169812018 @default.
• W1788116981 countsByYear W17881169812019 @default.
• W1788116981 countsByYear W17881169812020 @default.
• W1788116981 countsByYear W17881169812021 @default.
• W1788116981 countsByYear W17881169812022 @default.
• W1788116981 crossrefType "journal-article" @default.
• W1788116981 hasAuthorship W1788116981A5017620070 @default.
• W1788116981 hasAuthorship W1788116981A5023848615 @default.
• W1788116981 hasAuthorship W1788116981A5032152919 @default.
• W1788116981 hasAuthorship W1788116981A5036109780 @default.
• W1788116981 hasAuthorship W1788116981A5037916347 @default.
• W1788116981 hasAuthorship W1788116981A5040003588 @default.
• W1788116981 hasAuthorship W1788116981A5075876661 @default.
• W1788116981 hasAuthorship W1788116981A5090360163 @default.
• W1788116981 hasConcept C105702510 @default.
• W1788116981 hasConcept C105795698 @default.
• W1788116981 hasConcept C127313418 @default.
• W1788116981 hasConcept C127413603 @default.
• W1788116981 hasConcept C150077022 @default.
• W1788116981 hasConcept C151730666 @default.
• W1788116981 hasConcept C185592680 @default.
• W1788116981 hasConcept C187530423 @default.
• W1788116981 hasConcept C192562407 @default.
• W1788116981 hasConcept C204320433 @default.
• W1788116981 hasConcept C2776954882 @default.
• W1788116981 hasConcept C2778778583 @default.
• W1788116981 hasConcept C2780449318 @default.
• W1788116981 hasConcept C2983524802 @default.
• W1788116981 hasConcept C33923547 @default.
• W1788116981 hasConcept C42360764 @default.
• W1788116981 hasConcept C43617362 @default.
• W1788116981 hasConcept C48921125 @default.
• W1788116981 hasConcept C71924100 @default.
• W1788116981 hasConceptScore W1788116981C105702510 @default.
• W1788116981 hasConceptScore W1788116981C105795698 @default.
• W1788116981 hasConceptScore W1788116981C127313418 @default.
• W1788116981 hasConceptScore W1788116981C127413603 @default.
• W1788116981 hasConceptScore W1788116981C150077022 @default.
• W1788116981 hasConceptScore W1788116981C151730666 @default.
• W1788116981 hasConceptScore W1788116981C185592680 @default.
• W1788116981 hasConceptScore W1788116981C187530423 @default.
• W1788116981 hasConceptScore W1788116981C192562407 @default.
• W1788116981 hasConceptScore W1788116981C204320433 @default.
• W1788116981 hasConceptScore W1788116981C2776954882 @default.
• W1788116981 hasConceptScore W1788116981C2778778583 @default.
• W1788116981 hasConceptScore W1788116981C2780449318 @default.

• next