FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1792036402> ?p ?o ?g. }

• W1792036402 endingPage "335" @default.
• W1792036402 startingPage "327" @default.
• W1792036402 abstract "Transtracheal instillation of clinical isolate Klebsiella pneumoniae serotype 1 (KP1) into the lungs of rats resulted in the production of a characteristic, chronic lobar pneumonia. To further examine this phenomenon, two variants of this organism were employed in this experimental model. These variants differed markedly in capsule size, colony morphology, and in virulence, as determined by mouse lethality tests. The ability of these strains to establish a lobar pneumonia in rats correlated with the virulence of the respective organisms as monitored by intraperitoneal injection in mice. The 50% lethal doses in mice were 4.9 x 10(1) colony-forming units (CFU) for the more virulent KP1 strain (KP1-O) and 1.42 x 10(5) CFU for the less virulent variant (KP1-T). In the rat lung model, marked lung pathology was evident by day 6 with a KP1-O inoculum of 5 x 10(2) CFU, whereas KP1-T caused little or no lung pathology when delivered transtracheally at a concentration of 7 x 10(6) CFU. Two relatively nonvirulent variants of K. pneumoniae serotype 2 were also used in this rat lung model and were found not to produce a lobar pneumonia even when delivered in large doses. These results indicate that a chronic lobar pneumonia can be established in a rat model if the appropriate organism is employed and the virulence of K. pneumoniae injected intraperitoneally into mice is an excellent indicator of an organism's potential to cause lobar pneumonia in rats." @default.
• W1792036402 created "2016-06-24" @default.
• W1792036402 creator A5004385855 @default.
• W1792036402 creator A5037887048 @default.
• W1792036402 creator A5074683000 @default.
• W1792036402 date "1982-07-01" @default.
• W1792036402 modified "2023-10-02" @default.
• W1792036402 title "Lobar pneumonia in rats produced by clinical isolates of Klebsiella pneumoniae" @default.
• W1792036402 cites W111682225 @default.
• W1792036402 cites W1565712096 @default.
• W1792036402 cites W158601944 @default.
• W1792036402 cites W1909945092 @default.
• W1792036402 cites W19251271 @default.
• W1792036402 cites W1931237670 @default.
• W1792036402 cites W1951891676 @default.
• W1792036402 cites W1977802642 @default.
• W1792036402 cites W1996539884 @default.
• W1792036402 cites W2008650595 @default.
• W1792036402 cites W2009606659 @default.
• W1792036402 cites W2029178623 @default.
• W1792036402 cites W2035358742 @default.
• W1792036402 cites W2040578679 @default.
• W1792036402 cites W2056181672 @default.
• W1792036402 cites W2058613074 @default.
• W1792036402 cites W2105492199 @default.
• W1792036402 cites W2111357759 @default.
• W1792036402 cites W2120043451 @default.
• W1792036402 cites W2139276934 @default.
• W1792036402 cites W2142912549 @default.
• W1792036402 cites W2160650519 @default.
• W1792036402 cites W2163143152 @default.
• W1792036402 cites W2256756668 @default.
• W1792036402 cites W2262397211 @default.
• W1792036402 cites W2325981905 @default.
• W1792036402 cites W2411168089 @default.
• W1792036402 cites W2413402754 @default.
• W1792036402 cites W2798643531 @default.
• W1792036402 cites W3217730596 @default.
• W1792036402 cites W2992859777 @default.
• W1792036402 doi "https://doi.org/10.1128/iai.37.1.327-335.1982" @default.
• W1792036402 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/347530" @default.
• W1792036402 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7049951" @default.
• W1792036402 hasPublicationYear "1982" @default.
• W1792036402 type Work @default.
• W1792036402 sameAs 1792036402 @default.
• W1792036402 citedByCount "89" @default.
• W1792036402 countsByYear W17920364022012 @default.
• W1792036402 countsByYear W17920364022013 @default.
• W1792036402 countsByYear W17920364022014 @default.
• W1792036402 countsByYear W17920364022016 @default.
• W1792036402 countsByYear W17920364022017 @default.
• W1792036402 countsByYear W17920364022018 @default.
• W1792036402 countsByYear W17920364022021 @default.
• W1792036402 countsByYear W17920364022022 @default.
• W1792036402 countsByYear W17920364022023 @default.
• W1792036402 crossrefType "journal-article" @default.
• W1792036402 hasAuthorship W1792036402A5004385855 @default.
• W1792036402 hasAuthorship W1792036402A5037887048 @default.
• W1792036402 hasAuthorship W1792036402A5074683000 @default.
• W1792036402 hasBestOaLocation W17920364021 @default.
• W1792036402 hasConcept C10389963 @default.
• W1792036402 hasConcept C104317684 @default.
• W1792036402 hasConcept C126322002 @default.
• W1792036402 hasConcept C2776178081 @default.
• W1792036402 hasConcept C2776933286 @default.
• W1792036402 hasConcept C2777058267 @default.
• W1792036402 hasConcept C2777637488 @default.
• W1792036402 hasConcept C2777714996 @default.
• W1792036402 hasConcept C2777914695 @default.
• W1792036402 hasConcept C2777972467 @default.
• W1792036402 hasConcept C523546767 @default.
• W1792036402 hasConcept C54355233 @default.
• W1792036402 hasConcept C547475151 @default.
• W1792036402 hasConcept C55493867 @default.
• W1792036402 hasConcept C60987743 @default.
• W1792036402 hasConcept C71924100 @default.
• W1792036402 hasConcept C86803240 @default.
• W1792036402 hasConcept C89423630 @default.
• W1792036402 hasConceptScore W1792036402C10389963 @default.
• W1792036402 hasConceptScore W1792036402C104317684 @default.
• W1792036402 hasConceptScore W1792036402C126322002 @default.
• W1792036402 hasConceptScore W1792036402C2776178081 @default.
• W1792036402 hasConceptScore W1792036402C2776933286 @default.
• W1792036402 hasConceptScore W1792036402C2777058267 @default.
• W1792036402 hasConceptScore W1792036402C2777637488 @default.
• W1792036402 hasConceptScore W1792036402C2777714996 @default.
• W1792036402 hasConceptScore W1792036402C2777914695 @default.
• W1792036402 hasConceptScore W1792036402C2777972467 @default.
• W1792036402 hasConceptScore W1792036402C523546767 @default.
• W1792036402 hasConceptScore W1792036402C54355233 @default.
• W1792036402 hasConceptScore W1792036402C547475151 @default.
• W1792036402 hasConceptScore W1792036402C55493867 @default.
• W1792036402 hasConceptScore W1792036402C60987743 @default.
• W1792036402 hasConceptScore W1792036402C71924100 @default.
• W1792036402 hasConceptScore W1792036402C86803240 @default.
• W1792036402 hasConceptScore W1792036402C89423630 @default.
• W1792036402 hasIssue "1" @default.
• W1792036402 hasLocation W17920364021 @default.

• next