Matches in SemOpenAlex for { <https://semopenalex.org/work/W1792111761> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W1792111761 endingPage "E348" @default.
- W1792111761 startingPage "E343" @default.
- W1792111761 abstract "The effects of adrenalectomy and/or in vivo treatment with hydrocortisone acetate (HCA;5 mg X kg-1 X day-1) on lung growth were investigated in control and pneumonectomized rats of 250 g body wt. Left pneumonectomy (day 0) initiated rapid hyperplastic growth of the right lung, which was unaffected by HCA. Similarly, HCA had no effect on lung growth in unoperated control animals. Two weeks after pneumonectomy, right lung dry mass, protein, RNA, and DNA were equal to that in both lungs of unoperated rats. Adrenalectomy 5 days before (day -5) left pneumonectomy increased the rate and extent of right lung growth, but did not change its hyperplastic character. Continuous HCA treatment (days -5 to 14) prevented the adrenalectomy-mediated increase in postpneumonectomy lung growth. Early HCA dosing (days -5 to 6) of adrenalectomized-pneumonectomized animals suppressed lung growth to the pneumonectomy level, but from days 7 to 14 growth accelerated to the adrenalectomized-pneumonectomized rate. Conversely, late HCA, initiated when adrenalectomized-pneumonectomized animals had restored normal total lung mass (days 6 to 14), quickly reduced right lung growth to rates typical of unoperated controls. The latter effects were not observed unless continuous steroid treatment was provided throughout this interval. The data support a role for glucocorticosteroids in modulation of the accelerated compensatory lung growth initiated by partial resection of the tissue." @default.
- W1792111761 created "2016-06-24" @default.
- W1792111761 creator A5048880177 @default.
- W1792111761 creator A5048979512 @default.
- W1792111761 creator A5054706661 @default.
- W1792111761 date "1987-10-01" @default.
- W1792111761 modified "2023-09-27" @default.
- W1792111761 title "Control of compensatory lung growth by adrenal hormones" @default.
- W1792111761 cites W118895071 @default.
- W1792111761 doi "https://doi.org/10.1152/ajpendo.1987.253.4.e343" @default.
- W1792111761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2444112" @default.
- W1792111761 hasPublicationYear "1987" @default.
- W1792111761 type Work @default.
- W1792111761 sameAs 1792111761 @default.
- W1792111761 citedByCount "7" @default.
- W1792111761 countsByYear W17921117612012 @default.
- W1792111761 countsByYear W17921117612016 @default.
- W1792111761 countsByYear W17921117612021 @default.
- W1792111761 crossrefType "journal-article" @default.
- W1792111761 hasAuthorship W1792111761A5048880177 @default.
- W1792111761 hasAuthorship W1792111761A5048979512 @default.
- W1792111761 hasAuthorship W1792111761A5054706661 @default.
- W1792111761 hasConcept C126322002 @default.
- W1792111761 hasConcept C134018914 @default.
- W1792111761 hasConcept C2776121673 @default.
- W1792111761 hasConcept C2777589429 @default.
- W1792111761 hasConcept C2777714996 @default.
- W1792111761 hasConcept C2780087391 @default.
- W1792111761 hasConcept C2780091579 @default.
- W1792111761 hasConcept C71315377 @default.
- W1792111761 hasConcept C71924100 @default.
- W1792111761 hasConcept C86803240 @default.
- W1792111761 hasConceptScore W1792111761C126322002 @default.
- W1792111761 hasConceptScore W1792111761C134018914 @default.
- W1792111761 hasConceptScore W1792111761C2776121673 @default.
- W1792111761 hasConceptScore W1792111761C2777589429 @default.
- W1792111761 hasConceptScore W1792111761C2777714996 @default.
- W1792111761 hasConceptScore W1792111761C2780087391 @default.
- W1792111761 hasConceptScore W1792111761C2780091579 @default.
- W1792111761 hasConceptScore W1792111761C71315377 @default.
- W1792111761 hasConceptScore W1792111761C71924100 @default.
- W1792111761 hasConceptScore W1792111761C86803240 @default.
- W1792111761 hasIssue "4" @default.
- W1792111761 hasLocation W17921117611 @default.
- W1792111761 hasLocation W17921117612 @default.
- W1792111761 hasOpenAccess W1792111761 @default.
- W1792111761 hasPrimaryLocation W17921117611 @default.
- W1792111761 hasRelatedWork W1792111761 @default.
- W1792111761 hasRelatedWork W1970426690 @default.
- W1792111761 hasRelatedWork W1971238898 @default.
- W1792111761 hasRelatedWork W1989750494 @default.
- W1792111761 hasRelatedWork W2037145429 @default.
- W1792111761 hasRelatedWork W2040902964 @default.
- W1792111761 hasRelatedWork W2107664466 @default.
- W1792111761 hasRelatedWork W2108720656 @default.
- W1792111761 hasRelatedWork W2171404466 @default.
- W1792111761 hasRelatedWork W2401244076 @default.
- W1792111761 hasVolume "253" @default.
- W1792111761 isParatext "false" @default.
- W1792111761 isRetracted "false" @default.
- W1792111761 magId "1792111761" @default.
- W1792111761 workType "article" @default.