Matches in SemOpenAlex for { <https://semopenalex.org/work/W1793119713> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W1793119713 endingPage "5" @default.
- W1793119713 startingPage "701" @default.
- W1793119713 abstract "Laboratory test results in primary care are flagged as 'abnormal' when they fall outside a population-based Reference Interval (RI), typically generating many alerts with a low specificity. In order to decrease alert frequency while retaining clinical relevance, we developed a method to assess dynamic, patient-tailored RIs based on mixed-effects linear regression models. Potassium test results from primary care were used as proof-of-concept test bed. Clinical relevance was assessed via a survey administered to general practitioners (GPs). Overall, the dynamic, patient-tailored method and the combination of both methods flagged 20% and 36% fewer values as abnormal than the population-based method. Nineteen out of 43 invited GPs (44%) completed the survey. The population-based method yielded a better sensitivity than the patient-tailored and the combined methods (0.51 vs 0.41 and 0.38, respectively) but a lower PPV (0.66 vs 0.67 and 0.76, respectively). We conclude that a combination of population-based and patient-tailored RIs can improve the detection of abnormal laboratory results. We suggest that lab values outside both RIs be flagged with high priority in clinical practice." @default.
- W1793119713 created "2016-06-24" @default.
- W1793119713 creator A5009413839 @default.
- W1793119713 creator A5031083710 @default.
- W1793119713 creator A5039419132 @default.
- W1793119713 creator A5044012099 @default.
- W1793119713 creator A5059494163 @default.
- W1793119713 creator A5062702059 @default.
- W1793119713 date "2015-01-01" @default.
- W1793119713 modified "2023-09-23" @default.
- W1793119713 title "Development and preliminary validation of a dynamic, patient-tailored method to detect abnormal laboratory test results." @default.
- W1793119713 cites W125667916 @default.
- W1793119713 cites W1971614999 @default.
- W1793119713 cites W1980432185 @default.
- W1793119713 cites W2003694524 @default.
- W1793119713 cites W2049161346 @default.
- W1793119713 cites W2067749027 @default.
- W1793119713 cites W2081723834 @default.
- W1793119713 cites W2082549666 @default.
- W1793119713 cites W2116241811 @default.
- W1793119713 cites W2127579435 @default.
- W1793119713 cites W2135630562 @default.
- W1793119713 cites W2169468746 @default.
- W1793119713 cites W2181522674 @default.
- W1793119713 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26262142" @default.
- W1793119713 hasPublicationYear "2015" @default.
- W1793119713 type Work @default.
- W1793119713 sameAs 1793119713 @default.
- W1793119713 citedByCount "1" @default.
- W1793119713 countsByYear W17931197132017 @default.
- W1793119713 crossrefType "journal-article" @default.
- W1793119713 hasAuthorship W1793119713A5009413839 @default.
- W1793119713 hasAuthorship W1793119713A5031083710 @default.
- W1793119713 hasAuthorship W1793119713A5039419132 @default.
- W1793119713 hasAuthorship W1793119713A5044012099 @default.
- W1793119713 hasAuthorship W1793119713A5059494163 @default.
- W1793119713 hasAuthorship W1793119713A5062702059 @default.
- W1793119713 hasConcept C126322002 @default.
- W1793119713 hasConcept C151730666 @default.
- W1793119713 hasConcept C158154518 @default.
- W1793119713 hasConcept C17744445 @default.
- W1793119713 hasConcept C19527891 @default.
- W1793119713 hasConcept C199539241 @default.
- W1793119713 hasConcept C2777267654 @default.
- W1793119713 hasConcept C2908647359 @default.
- W1793119713 hasConcept C2984752397 @default.
- W1793119713 hasConcept C41008148 @default.
- W1793119713 hasConcept C512399662 @default.
- W1793119713 hasConcept C63363279 @default.
- W1793119713 hasConcept C71924100 @default.
- W1793119713 hasConcept C86803240 @default.
- W1793119713 hasConcept C99454951 @default.
- W1793119713 hasConceptScore W1793119713C126322002 @default.
- W1793119713 hasConceptScore W1793119713C151730666 @default.
- W1793119713 hasConceptScore W1793119713C158154518 @default.
- W1793119713 hasConceptScore W1793119713C17744445 @default.
- W1793119713 hasConceptScore W1793119713C19527891 @default.
- W1793119713 hasConceptScore W1793119713C199539241 @default.
- W1793119713 hasConceptScore W1793119713C2777267654 @default.
- W1793119713 hasConceptScore W1793119713C2908647359 @default.
- W1793119713 hasConceptScore W1793119713C2984752397 @default.
- W1793119713 hasConceptScore W1793119713C41008148 @default.
- W1793119713 hasConceptScore W1793119713C512399662 @default.
- W1793119713 hasConceptScore W1793119713C63363279 @default.
- W1793119713 hasConceptScore W1793119713C71924100 @default.
- W1793119713 hasConceptScore W1793119713C86803240 @default.
- W1793119713 hasConceptScore W1793119713C99454951 @default.
- W1793119713 hasLocation W17931197131 @default.
- W1793119713 hasOpenAccess W1793119713 @default.
- W1793119713 hasPrimaryLocation W17931197131 @default.
- W1793119713 hasRelatedWork W2139529285 @default.
- W1793119713 hasRelatedWork W3120060370 @default.
- W1793119713 hasVolume "216" @default.
- W1793119713 isParatext "false" @default.
- W1793119713 isRetracted "false" @default.
- W1793119713 magId "1793119713" @default.
- W1793119713 workType "article" @default.