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- W1794556764 abstract "In response to the Case Report on profound anemia in the March 2006 issue of Canadian Family Physician,1 I question the need to transfuse 3 units of packed red blood cells to a 44-year-old woman who is asymptomatic except for nonspecific “fatigue before menstruation.”1 As outlined in an article published in the Canadian Medical Association Journal,2 there is little evidence to support transfusions for chronic illnesses where there is no immediate cardiac threat from inadequate oxygen delivery to tissue. The following points are supported by level II evidence.Red blood cell transfusions should be administered primarily to prevent or alleviate symptoms, signs, or morbidity due to inadequate oxygen delivery to tissue (resulting from low red blood cell mass).There is no single value of hemoglobin concentration that justifies or requires transfusion; an evaluation of the patient’s clinical situation should also be a factor in the decision.In the setting of acute blood loss, red blood cell transfusion should not be used to expand vascular volume when oxygen-carrying capacity is adequate.Anemia should not be treated with red blood cell transfusions if alternative therapies with fewer potential risks are available and appropriate.Clearly alternative treatments were available for this patient that would also have been successful, such as iron and folate therapy. As well, I think it important to mention investigations for intestinal helminths as a possible cause of anemia in refugees, including Ascaris lumbricoides, Trichuris trichiura, and hookworms, among others." @default.
- W1794556764 created "2016-06-24" @default.
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- W1794556764 date "2006-05-01" @default.
- W1794556764 modified "2023-09-26" @default.
- W1794556764 title "Other treatments for profound anemia." @default.
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