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- W179475863 abstract "Initiation of DNA replication is tightly regulated to ensure that it occurs once and only once in each cell cycle. This coupling relies on the coordinated activities of the cyclin-dependent kinase, a central component of the cell cycle engine, and the kinase Cdc7. These kinases act on proteins of the pre-replication complex (preRC) at replication origins to promote the loading of additional proteins which initiate DNA unwinding and DNA synthesis. CDK also ensures that the preRC cannot be re-assembled until after cell division has occurred." @default.
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- W179475863 date "2013-01-01" @default.
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- W179475863 title "Cell Cycle: Control of Entry and Progression through S Phase" @default.
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- W179475863 doi "https://doi.org/10.1016/b978-0-12-378630-2.00418-7" @default.
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