FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1795771796> ?p ?o ?g. }

• W1795771796 endingPage "476" @default.
• W1795771796 startingPage "463" @default.
• W1795771796 abstract "Abstract Saccharomyces cerevisiae has two haploid cell types, a and alpha, each of which produces a unique set of proteins that participate in the mating process. We sought to determine the minimum set of proteins that must be expressed to allow mating and to confer specificity. We show that the capacity to synthesize alpha-factor pheromone and a-factor receptor is sufficient to allow mating by mat alpha 1 mutants, mutants that normally do not express any alpha- or a-specific products. Likewise, the capacity to synthesize a-factor receptor and alpha-factor pheromone is sufficient to allow a ste2 ste6 mutants, which do not produce the normal a cell pheromone and receptor, to mate with wild-type a cells. Thus, the a-factor receptor and alpha-factor pheromone constitute the minimum set of alpha-specific proteins that must be produced to allow mating as an alpha cell. Further evidence that the pheromones and pheromone receptors are important determinants of mating specificity comes from studies with mat alpha 2 mutants, cells that simultaneously express both pheromones and both receptors. We created a series of strains that express different combinations of pheromones and receptors in a mat alpha 2 background. These constructions reveal that mat alpha 2 mutants can be made to mate as either a cells or as alpha cells by causing them to express only the pheromone and receptor set appropriate for a particular cell type. Moreover, these studies show that the inability of mat alpha 2 mutants to respond to either pheromone is a consequence of two phenomena: adaptation to an autocrine response to the pheromones they secrete and interference with response to alpha factor by the a-factor receptor." @default.
• W1795771796 created "2016-06-24" @default.
• W1795771796 creator A5008279233 @default.
• W1795771796 creator A5032355333 @default.
• W1795771796 date "1989-03-01" @default.
• W1795771796 modified "2023-10-15" @default.
• W1795771796 title "Pheromones and pheromone receptors are the primary determinants of mating specificity in the yeast Saccharomyces cerevisiae." @default.
• W1795771796 cites W1488192310 @default.
• W1795771796 cites W1509044914 @default.
• W1795771796 cites W1511714820 @default.
• W1795771796 cites W1537782690 @default.
• W1795771796 cites W1547429114 @default.
• W1795771796 cites W1559808711 @default.
• W1795771796 cites W1575868449 @default.
• W1795771796 cites W1597307589 @default.
• W1795771796 cites W1645643399 @default.
• W1795771796 cites W1749919947 @default.
• W1795771796 cites W1781717284 @default.
• W1795771796 cites W1804112110 @default.
• W1795771796 cites W1840761410 @default.
• W1795771796 cites W1853445387 @default.
• W1795771796 cites W1949341109 @default.
• W1795771796 cites W1978088045 @default.
• W1795771796 cites W1996081447 @default.
• W1795771796 cites W2005115290 @default.
• W1795771796 cites W2005173649 @default.
• W1795771796 cites W2017849731 @default.
• W1795771796 cites W2026070522 @default.
• W1795771796 cites W2027469361 @default.
• W1795771796 cites W2047684202 @default.
• W1795771796 cites W2049406279 @default.
• W1795771796 cites W2050611086 @default.
• W1795771796 cites W2052538982 @default.
• W1795771796 cites W2053471076 @default.
• W1795771796 cites W2054823031 @default.
• W1795771796 cites W2056240197 @default.
• W1795771796 cites W2063190856 @default.
• W1795771796 cites W2063669071 @default.
• W1795771796 cites W2072359314 @default.
• W1795771796 cites W2078653964 @default.
• W1795771796 cites W2084292111 @default.
• W1795771796 cites W2090051807 @default.
• W1795771796 cites W2092667440 @default.
• W1795771796 cites W2100611378 @default.
• W1795771796 cites W2102106222 @default.
• W1795771796 cites W2116443124 @default.
• W1795771796 cites W2120875352 @default.
• W1795771796 cites W2122607854 @default.
• W1795771796 cites W2128093756 @default.
• W1795771796 cites W2138006485 @default.
• W1795771796 cites W2141669602 @default.
• W1795771796 cites W2169973516 @default.
• W1795771796 cites W2170771663 @default.
• W1795771796 cites W2172372808 @default.
• W1795771796 cites W2308345180 @default.
• W1795771796 cites W2489213573 @default.
• W1795771796 doi "https://doi.org/10.1093/genetics/121.3.463" @default.
• W1795771796 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1203633" @default.
• W1795771796 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2653961" @default.
• W1795771796 hasPublicationYear "1989" @default.
• W1795771796 type Work @default.
• W1795771796 sameAs 1795771796 @default.
• W1795771796 citedByCount "68" @default.
• W1795771796 countsByYear W17957717962012 @default.
• W1795771796 countsByYear W17957717962013 @default.
• W1795771796 countsByYear W17957717962014 @default.
• W1795771796 countsByYear W17957717962015 @default.
• W1795771796 countsByYear W17957717962018 @default.
• W1795771796 countsByYear W17957717962020 @default.
• W1795771796 countsByYear W17957717962021 @default.
• W1795771796 countsByYear W17957717962022 @default.
• W1795771796 countsByYear W17957717962023 @default.
• W1795771796 crossrefType "journal-article" @default.
• W1795771796 hasAuthorship W1795771796A5008279233 @default.
• W1795771796 hasAuthorship W1795771796A5032355333 @default.
• W1795771796 hasBestOaLocation W17957717961 @default.
• W1795771796 hasConcept C104317684 @default.
• W1795771796 hasConcept C143065580 @default.
• W1795771796 hasConcept C170493617 @default.
• W1795771796 hasConcept C198348125 @default.
• W1795771796 hasConcept C2777328355 @default.
• W1795771796 hasConcept C2777576037 @default.
• W1795771796 hasConcept C2779222958 @default.
• W1795771796 hasConcept C46909000 @default.
• W1795771796 hasConcept C514575182 @default.
• W1795771796 hasConcept C54355233 @default.
• W1795771796 hasConcept C64778439 @default.
• W1795771796 hasConcept C86803240 @default.
• W1795771796 hasConcept C95444343 @default.
• W1795771796 hasConceptScore W1795771796C104317684 @default.
• W1795771796 hasConceptScore W1795771796C143065580 @default.
• W1795771796 hasConceptScore W1795771796C170493617 @default.
• W1795771796 hasConceptScore W1795771796C198348125 @default.
• W1795771796 hasConceptScore W1795771796C2777328355 @default.
• W1795771796 hasConceptScore W1795771796C2777576037 @default.
• W1795771796 hasConceptScore W1795771796C2779222958 @default.
• W1795771796 hasConceptScore W1795771796C46909000 @default.
• W1795771796 hasConceptScore W1795771796C514575182 @default.

• next