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- W1796140256 abstract "T H E multitude of observations67 ‘1 25 concerning abnormal hemorrhagic states during pregnancy usually refers to the syndrome of afibrinogenemia or hypofibrinogenemia. The pathogenetic concept of a defibrinating syndromez5 in which fibrinogen is consumed as the resuit of the autoextraction of thromboplastin has been substantiated by a variety of experimental observations, but the part which fibrinolysis plays in such cases remains open to discussion. This is partly because, in the cases observed to date, exact determinations of fibrinolytic activity have not been made. In only a few cases has blood been taken and investigated at frequent intervals in the acute phase, In addition, clinical determination of fibrinolysis is not yet satisfactory and particularly the socalled rapid methods (clot observation test and others)16 give no indication of any associated fibrinolytic activity.23 Therefore, whether, and to what extent, fibrinolysis is a reactive process to the pathologic fibrin deposition or whether it is primarily of pathogenetic importance in hemorrhagic diathesis associated with pregnancy remains an open question. Clinical and analytical findings, in a case of abnormal obstetric bleeding recently ob-" @default.
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- W1796140256 date "1961-09-01" @default.
- W1796140256 modified "2023-09-26" @default.
- W1796140256 title "Fibrinogenolysis as a cause of obstetric hemorrhage" @default.
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- W1796140256 doi "https://doi.org/10.1016/0002-9378(61)90281-2" @default.
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