FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1796144808> ?p ?o ?g. }

• W1796144808 endingPage "C1497" @default.
• W1796144808 startingPage "C1485" @default.
• W1796144808 abstract "The purinergic regulation of ciliary activity was studied using small, continuously superfused explants of human nasal epithelium. The P2Y(2) purinoceptor (P2Y(2)-R) was identified as the major purinoceptor regulating ciliary beat frequency (CBF); UTP (EC(50) = 4.7 microM), ATP, and adenosine-5'-O-(3-thiotriphosphate) elicited similar maximal responses, approximately twofold over baseline. ATP, however, elicited a post-peak sustained plateau in CBF (1.83 +/- 0.1-fold), whereas the post-peak CBF response to UTP declined over 15 min to a low-level plateau (1.36 +/- 0.16-fold). UDP also stimulated ciliary beating, probably via P2Y(6)-R, with a maximal effect approximately one-half that elicited by P2Y(2)-R stimulation. Not indicated were P2Y(1)-R-, P2Y(4)-R-, or P2Y(11)-R-mediated effects. A(2B)-receptor agonists elicited sustained responses in CBF approximately equal to those from UTP/ATP [5'-(N-ethylcarboxamido)adenosine, EC(50) = 0.09 microM; adenosine, EC(50) = 0.7 microM]. Surprisingly, ADP elicited a sustained stimulation in CBF. The ADP effect and the post-peak sustained portion of the ATP response in CBF were inhibited by the A(2)-R antagonist 8-(p-sulfophenyl)theophylline. Hence, ATP affects ciliary activity through P2Y(2)-R and, after an apparent ectohydrolysis to adenosine, through A(2B)AR." @default.
• W1796144808 created "2016-06-24" @default.
• W1796144808 creator A5005672335 @default.
• W1796144808 creator A5033028139 @default.
• W1796144808 creator A5066878640 @default.
• W1796144808 date "2001-06-01" @default.
• W1796144808 modified "2023-10-18" @default.
• W1796144808 title "Differential effects of UTP, ATP, and adenosine on ciliary activity of human nasal epithelial cells" @default.
• W1796144808 cites W1224852380 @default.
• W1796144808 cites W1499941256 @default.
• W1796144808 cites W1573846225 @default.
• W1796144808 cites W1578187871 @default.
• W1796144808 cites W1607766476 @default.
• W1796144808 cites W1627680225 @default.
• W1796144808 cites W1680485768 @default.
• W1796144808 cites W1774349284 @default.
• W1796144808 cites W1842328399 @default.
• W1796144808 cites W1904668215 @default.
• W1796144808 cites W1965484171 @default.
• W1796144808 cites W1967675162 @default.
• W1796144808 cites W1976950999 @default.
• W1796144808 cites W1978624367 @default.
• W1796144808 cites W1980041137 @default.
• W1796144808 cites W1980927246 @default.
• W1796144808 cites W1981183509 @default.
• W1796144808 cites W1982921814 @default.
• W1796144808 cites W1987778629 @default.
• W1796144808 cites W1993569708 @default.
• W1796144808 cites W1993761825 @default.
• W1796144808 cites W1999274391 @default.
• W1796144808 cites W2003810545 @default.
• W1796144808 cites W2008352187 @default.
• W1796144808 cites W2009638458 @default.
• W1796144808 cites W2013920361 @default.
• W1796144808 cites W2029400868 @default.
• W1796144808 cites W2034861930 @default.
• W1796144808 cites W2036619732 @default.
• W1796144808 cites W2039689709 @default.
• W1796144808 cites W2045817586 @default.
• W1796144808 cites W2046600619 @default.
• W1796144808 cites W2055497515 @default.
• W1796144808 cites W2056302193 @default.
• W1796144808 cites W2056395380 @default.
• W1796144808 cites W2061944559 @default.
• W1796144808 cites W2067580682 @default.
• W1796144808 cites W2076205950 @default.
• W1796144808 cites W2076722514 @default.
• W1796144808 cites W2082370179 @default.
• W1796144808 cites W2086850748 @default.
• W1796144808 cites W2087582180 @default.
• W1796144808 cites W2087714421 @default.
• W1796144808 cites W2094319340 @default.
• W1796144808 cites W2104234386 @default.
• W1796144808 cites W2109173245 @default.
• W1796144808 cites W2111395353 @default.
• W1796144808 cites W2113565576 @default.
• W1796144808 cites W2116985644 @default.
• W1796144808 cites W2123382745 @default.
• W1796144808 cites W2140327830 @default.
• W1796144808 cites W2149658463 @default.
• W1796144808 cites W2160606813 @default.
• W1796144808 cites W2189467740 @default.
• W1796144808 cites W2338243080 @default.
• W1796144808 cites W2434593122 @default.
• W1796144808 cites W2472027441 @default.
• W1796144808 cites W34123101 @default.
• W1796144808 cites W4233719888 @default.
• W1796144808 doi "https://doi.org/10.1152/ajpcell.2001.280.6.c1485" @default.
• W1796144808 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11350744" @default.
• W1796144808 hasPublicationYear "2001" @default.
• W1796144808 type Work @default.
• W1796144808 sameAs 1796144808 @default.
• W1796144808 citedByCount "114" @default.
• W1796144808 countsByYear W17961448082012 @default.
• W1796144808 countsByYear W17961448082013 @default.
• W1796144808 countsByYear W17961448082014 @default.
• W1796144808 countsByYear W17961448082015 @default.
• W1796144808 countsByYear W17961448082016 @default.
• W1796144808 countsByYear W17961448082017 @default.
• W1796144808 countsByYear W17961448082018 @default.
• W1796144808 countsByYear W17961448082019 @default.
• W1796144808 countsByYear W17961448082020 @default.
• W1796144808 countsByYear W17961448082021 @default.
• W1796144808 countsByYear W17961448082022 @default.
• W1796144808 countsByYear W17961448082023 @default.
• W1796144808 crossrefType "journal-article" @default.
• W1796144808 hasAuthorship W1796144808A5005672335 @default.
• W1796144808 hasAuthorship W1796144808A5033028139 @default.
• W1796144808 hasAuthorship W1796144808A5066878640 @default.
• W1796144808 hasConcept C126322002 @default.
• W1796144808 hasConcept C134018914 @default.
• W1796144808 hasConcept C160225129 @default.
• W1796144808 hasConcept C170493617 @default.
• W1796144808 hasConcept C185592680 @default.
• W1796144808 hasConcept C24998067 @default.
• W1796144808 hasConcept C2776991684 @default.
• W1796144808 hasConcept C2778095195 @default.
• W1796144808 hasConcept C2778938600 @default.

• next