Matches in SemOpenAlex for { <https://semopenalex.org/work/W1796259460> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W1796259460 endingPage "7" @default.
- W1796259460 startingPage "253" @default.
- W1796259460 abstract "Although chemokines, as chemotactic factors, were already known in 70's of the past century, it was only the progress in molecular biology, genetics and immunology which occurred in the past few years that opened the way to discover new molecules, their chemical structure and biological functions. Fkn (fractalkine, CX3CL1) is a unique chemokine and the only representative of CX3C group. It exists as a membrane-bound and soluble form. It interacts with cells expressing CX3CR1, a G-coupled protein receptor. The polymorphism of CX3CR1 gene modulates Fkn affinity to its receptror, which influences the risk of development and progression of various diseases. Its unique character is determined by its functions. Fkn is not only a chemotactic factor, but it also participates in leukocyte trafficking, adhesion and cytotoxic activities, modulates expression of cytokines, adhesion molecules, free oxygen radicals, iNOS and influences apoptosis. Its elucidation should not only help understanding of molecular events occurring in many autoimmune inflammatory, neoplasmatic diseases, but would allow to use Fkn, its receptor, or anti-Fkn antibodies in treatment of those diseases." @default.
- W1796259460 created "2016-06-24" @default.
- W1796259460 creator A5007610136 @default.
- W1796259460 creator A5038844903 @default.
- W1796259460 creator A5047875737 @default.
- W1796259460 creator A5068064264 @default.
- W1796259460 creator A5084368458 @default.
- W1796259460 date "2009-03-01" @default.
- W1796259460 modified "2023-09-25" @default.
- W1796259460 title "[Fractalkine--structure, functions and biological activity]." @default.
- W1796259460 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19388544" @default.
- W1796259460 hasPublicationYear "2009" @default.
- W1796259460 type Work @default.
- W1796259460 sameAs 1796259460 @default.
- W1796259460 citedByCount "1" @default.
- W1796259460 countsByYear W17962594602017 @default.
- W1796259460 crossrefType "journal-article" @default.
- W1796259460 hasAuthorship W1796259460A5007610136 @default.
- W1796259460 hasAuthorship W1796259460A5038844903 @default.
- W1796259460 hasAuthorship W1796259460A5047875737 @default.
- W1796259460 hasAuthorship W1796259460A5068064264 @default.
- W1796259460 hasAuthorship W1796259460A5084368458 @default.
- W1796259460 hasConcept C12823836 @default.
- W1796259460 hasConcept C13373296 @default.
- W1796259460 hasConcept C159654299 @default.
- W1796259460 hasConcept C16224149 @default.
- W1796259460 hasConcept C170493617 @default.
- W1796259460 hasConcept C185592680 @default.
- W1796259460 hasConcept C203014093 @default.
- W1796259460 hasConcept C31179232 @default.
- W1796259460 hasConcept C54166955 @default.
- W1796259460 hasConcept C54355233 @default.
- W1796259460 hasConcept C82321936 @default.
- W1796259460 hasConcept C86803240 @default.
- W1796259460 hasConcept C95444343 @default.
- W1796259460 hasConceptScore W1796259460C12823836 @default.
- W1796259460 hasConceptScore W1796259460C13373296 @default.
- W1796259460 hasConceptScore W1796259460C159654299 @default.
- W1796259460 hasConceptScore W1796259460C16224149 @default.
- W1796259460 hasConceptScore W1796259460C170493617 @default.
- W1796259460 hasConceptScore W1796259460C185592680 @default.
- W1796259460 hasConceptScore W1796259460C203014093 @default.
- W1796259460 hasConceptScore W1796259460C31179232 @default.
- W1796259460 hasConceptScore W1796259460C54166955 @default.
- W1796259460 hasConceptScore W1796259460C54355233 @default.
- W1796259460 hasConceptScore W1796259460C82321936 @default.
- W1796259460 hasConceptScore W1796259460C86803240 @default.
- W1796259460 hasConceptScore W1796259460C95444343 @default.
- W1796259460 hasIssue "153" @default.
- W1796259460 hasLocation W17962594601 @default.
- W1796259460 hasOpenAccess W1796259460 @default.
- W1796259460 hasPrimaryLocation W17962594601 @default.
- W1796259460 hasRelatedWork W1460931276 @default.
- W1796259460 hasRelatedWork W1631597983 @default.
- W1796259460 hasRelatedWork W1700738039 @default.
- W1796259460 hasRelatedWork W1741110499 @default.
- W1796259460 hasRelatedWork W1966460849 @default.
- W1796259460 hasRelatedWork W2027521196 @default.
- W1796259460 hasRelatedWork W2105016136 @default.
- W1796259460 hasRelatedWork W2110301589 @default.
- W1796259460 hasRelatedWork W2113355655 @default.
- W1796259460 hasRelatedWork W2182116925 @default.
- W1796259460 hasRelatedWork W2313748147 @default.
- W1796259460 hasRelatedWork W2357323564 @default.
- W1796259460 hasRelatedWork W23809908 @default.
- W1796259460 hasRelatedWork W2466411051 @default.
- W1796259460 hasRelatedWork W2727556688 @default.
- W1796259460 hasRelatedWork W2961429180 @default.
- W1796259460 hasRelatedWork W3016461994 @default.
- W1796259460 hasRelatedWork W3110192767 @default.
- W1796259460 hasRelatedWork W56956580 @default.
- W1796259460 hasRelatedWork W186398044 @default.
- W1796259460 hasVolume "26" @default.
- W1796259460 isParatext "false" @default.
- W1796259460 isRetracted "false" @default.
- W1796259460 magId "1796259460" @default.
- W1796259460 workType "article" @default.