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• W179636839 abstract "AbstractThe decision to flower and commit to the reproductive phase requires that plants remember seasonal cues and keep a clock on their developmental age. Molecular memories have been explained by the bistable expression of genes. Bistable genes are switched from an expressed to a repressed state or vice versa in response to a primary stimulus, which is not required to maintain the switched state. Alterations in chromatin structure, orchestrated by covalent modifications of histones, are part of the molecular mechanism leading to bistable gene expression. For histone modifications that play a crucial role in molecular memories, the term “epigenetic chromatin marks” applies since bistable states can be maintained throughout mitosis. In the following chapter, we will first outline the regulation of the floral repressor FLOWERING LOCUS C (FLC) of Arabidopsis thaliana, for which the impact of chromatin modification on the molecular memory has been well studied. Differences in the regulation of the FLC and its ortholog PERPETUAL FLOWERING 1 from Arabis alpina, a perennial relative of A. thaliana, are discussed. Last, the impact of chromatin structure on the regulation of FLOWERING LOCUS T (FT) is presented to illustrate that chromatin regulation can be important in regulatory networks that do not require bistability.KeywordsShort Vegetative PhaseVernalization ResponseMolecular MemoryH3K27me3 TargetGibberellic Acid PathwayThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
• W179636839 created "2016-06-24" @default.
• W179636839 creator A5021080298 @default.
• W179636839 creator A5052390952 @default.
• W179636839 date "2013-01-01" @default.
• W179636839 modified "2023-10-12" @default.
• W179636839 title "Epigenetic Control of Flowering Time" @default.
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