Matches in SemOpenAlex for { <https://semopenalex.org/work/W1796716382> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W1796716382 abstract "The objective of present investigation was to separate, identify, and characterize the degradation products of lamotrigine under hydrolytic, oxidative, photolytic, and thermal stress conditions as per International Conference on Harmonization (ICH) guideline Q1A (R2). The drug underwent degradation under acidic, basic, and oxidative stress, while it was stable in photolytic and thermal stress conditions. A total four degradation products were formed which were separated by using HPLC on C18 column using gradient elution program. A complete mass fragmentation pattern of the drug was first established with the help of LC-MS/MS studies. The stressed samples were subjected to LC-MS/MS studies. The obtained mass spectral data were employed to characterize three degradation products and assign structures. Complete information was used to establish the degradation pathway of the drug. The degradation products were identified as 3-amino-6-(2, 3-dichlorophenyl)-1, 2, 4-triazin-5(4H)-one, 6-(2, 3-Dichloro-phenyl)-2..." @default.
- W1796716382 created "2016-06-24" @default.
- W1796716382 creator A5008779826 @default.
- W1796716382 creator A5013254784 @default.
- W1796716382 creator A5057148661 @default.
- W1796716382 date "2012-10-01" @default.
- W1796716382 modified "2023-09-27" @default.
- W1796716382 title "LC, LC-MS/MS STUDIES FOR IDENTIFICATION AND CHARACTERIZATION OF DEGRADATION PRODUCTS OF LAMOTRIGINE AND ESTABLISHMENT OF MECHANISTIC APPROACH TOWARDS DEGRADATION" @default.
- W1796716382 cites W1974297313 @default.
- W1796716382 cites W1975714885 @default.
- W1796716382 cites W1998242492 @default.
- W1796716382 cites W2015957293 @default.
- W1796716382 cites W2034184417 @default.
- W1796716382 cites W2038440652 @default.
- W1796716382 cites W2064235912 @default.
- W1796716382 doi "https://doi.org/10.1080/10826076.2011.629395" @default.
- W1796716382 hasPublicationYear "2012" @default.
- W1796716382 type Work @default.
- W1796716382 sameAs 1796716382 @default.
- W1796716382 citedByCount "1" @default.
- W1796716382 countsByYear W17967163822014 @default.
- W1796716382 crossrefType "journal-article" @default.
- W1796716382 hasAuthorship W1796716382A5008779826 @default.
- W1796716382 hasAuthorship W1796716382A5013254784 @default.
- W1796716382 hasAuthorship W1796716382A5057148661 @default.
- W1796716382 hasConcept C111919701 @default.
- W1796716382 hasConcept C124681953 @default.
- W1796716382 hasConcept C162356407 @default.
- W1796716382 hasConcept C178790620 @default.
- W1796716382 hasConcept C179998833 @default.
- W1796716382 hasConcept C185592680 @default.
- W1796716382 hasConcept C191015642 @default.
- W1796716382 hasConcept C2777682752 @default.
- W1796716382 hasConcept C2779679103 @default.
- W1796716382 hasConcept C3017686574 @default.
- W1796716382 hasConcept C41008148 @default.
- W1796716382 hasConcept C43617362 @default.
- W1796716382 hasConcept C45188465 @default.
- W1796716382 hasConcept C48333953 @default.
- W1796716382 hasConcept C64489805 @default.
- W1796716382 hasConcept C76155785 @default.
- W1796716382 hasConcept C94412978 @default.
- W1796716382 hasConceptScore W1796716382C111919701 @default.
- W1796716382 hasConceptScore W1796716382C124681953 @default.
- W1796716382 hasConceptScore W1796716382C162356407 @default.
- W1796716382 hasConceptScore W1796716382C178790620 @default.
- W1796716382 hasConceptScore W1796716382C179998833 @default.
- W1796716382 hasConceptScore W1796716382C185592680 @default.
- W1796716382 hasConceptScore W1796716382C191015642 @default.
- W1796716382 hasConceptScore W1796716382C2777682752 @default.
- W1796716382 hasConceptScore W1796716382C2779679103 @default.
- W1796716382 hasConceptScore W1796716382C3017686574 @default.
- W1796716382 hasConceptScore W1796716382C41008148 @default.
- W1796716382 hasConceptScore W1796716382C43617362 @default.
- W1796716382 hasConceptScore W1796716382C45188465 @default.
- W1796716382 hasConceptScore W1796716382C48333953 @default.
- W1796716382 hasConceptScore W1796716382C64489805 @default.
- W1796716382 hasConceptScore W1796716382C76155785 @default.
- W1796716382 hasConceptScore W1796716382C94412978 @default.
- W1796716382 hasLocation W17967163821 @default.
- W1796716382 hasOpenAccess W1796716382 @default.
- W1796716382 hasPrimaryLocation W17967163821 @default.
- W1796716382 hasRelatedWork W1506783248 @default.
- W1796716382 hasRelatedWork W1642927324 @default.
- W1796716382 hasRelatedWork W1859249089 @default.
- W1796716382 hasRelatedWork W1978116499 @default.
- W1796716382 hasRelatedWork W2012977761 @default.
- W1796716382 hasRelatedWork W2024110230 @default.
- W1796716382 hasRelatedWork W2028320381 @default.
- W1796716382 hasRelatedWork W2041149153 @default.
- W1796716382 hasRelatedWork W2043197060 @default.
- W1796716382 hasRelatedWork W2044144103 @default.
- W1796716382 hasRelatedWork W2062369079 @default.
- W1796716382 hasRelatedWork W2076285861 @default.
- W1796716382 hasRelatedWork W2097554992 @default.
- W1796716382 hasRelatedWork W2113036296 @default.
- W1796716382 hasRelatedWork W2131240425 @default.
- W1796716382 hasRelatedWork W2884659652 @default.
- W1796716382 hasRelatedWork W2987557564 @default.
- W1796716382 hasRelatedWork W3112417907 @default.
- W1796716382 hasRelatedWork W3138638780 @default.
- W1796716382 hasRelatedWork W2741752258 @default.
- W1796716382 isParatext "false" @default.
- W1796716382 isRetracted "false" @default.
- W1796716382 magId "1796716382" @default.
- W1796716382 workType "article" @default.