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- W179718867 abstract "To study the relation between cadmium and the itai-itai disease, cadmium was fed to rats. By continued determination of the amounts of calcium received from the diet and excreted in feces and urine, we could quantitatively trace the changes in the balance of calcium metabolism in the rats effected by cadmium. 30-100 ppM of cadmium mixed in a calcium-deficient diet resulted in a significant loss of calcium from the rat bone with much more fecal excretion of calcium than that gained from the diet. The urinary excretion of calcium, however, was in negligible quantity in the calculation of the balance and was rather decreased by cadmium. These results indicated that the calcium lost from rat bones is excreted in feces instead of urine, and so do not support the hypothesis that the bone changes are caused by renal tubular dysfunction. Instead it favored the view that the loss of calcium is due to lowered absorption of calcium and to its high excretion from digestive organs. 17 references, 5 figures, 5 tables." @default.
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- W179718867 date "1973-01-01" @default.
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- W179718867 title "Effects of cadmium on calcium metabolism of rats" @default.
- W179718867 hasPublicationYear "1973" @default.
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