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• W1798188575 abstract "Oxidative stress plays a role in Alzheimer's disease (AD) with elevated levels being present in tissues such as brain, plasma, and cerebrospinal fluid. The role of oxidative stress in the immune system of AD is less established. Therefore, we measured protein markers of oxidative stress—protein car bonyls (PCO) and 3-nitrotyrosine (3NT)—in CD90+ T-cells of a double-transgenic AD mouse model. Higher levels of PCO and 3NT were detected in amyloid-β protein precursor/presenilin-1 (AβPP/PS-1) mice and increased with disease progression. These studies provide evidence that oxidative stress in the immune system may be useful for understanding disease pathogenesis." @default.
• W1798188575 created "2016-06-24" @default.
• W1798188575 creator A5009725612 @default.
• W1798188575 creator A5056074050 @default.
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• W1798188575 date "2013-10-10" @default.
• W1798188575 modified "2023-09-25" @default.
• W1798188575 title "Oxidative Stress in CD90+ T-cells of AβPP/PS-1 Transgenic Mice" @default.
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• W1798188575 doi "https://doi.org/10.3233/jad-130665" @default.
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