FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1799025303> ?p ?o ?g. }

• W1799025303 endingPage "4851" @default.
• W1799025303 startingPage "4846" @default.
• W1799025303 abstract "Squamous differentiation of rabbit tracheal epithelial cells is accompanied by an approximately 50-fold increase in the activity of type I (epidermal) transglutaminase, while the levels of type II (tissue) transglutaminase remain almost undetectable. To identify a cDNA encoding type I transglutaminase, we screened a library of cDNA clones prepared from poly(A)+ RNA isolated from squamous-differentiated rabbit tracheal epithelial cells. Four overlapping clones (represented by clone pTG-7) which span a range of 2.8 kilobases were identified; partial sequencing of pTG-7 indicated that it encodes a transglutaminaselike protein. pTG-7 hybridized to a 3.6-kilobase mRNA which is distinct from that for type II transglutaminase. pTG-7 mRNA levels were low in proliferative cells, increased dramatically in squamous-differentiated cells, and could be further enhanced by growth of the cells in high concentrations (2 mM) of calcium ions. Retinoic acid, which blocks the expression of the squamous phenotype, prevented this increase in pTG-7 mRNA levels. These changes in levels of pTG-7 mRNA parallel the changes in type I transglutaminase activity observed under similar culture conditions. These data indicate that pTG-7 encodes the mRNA for transglutaminase type I and that expression of this mRNA is negatively regulated by retinoic acid." @default.
• W1799025303 created "2016-06-24" @default.
• W1799025303 creator A5006295693 @default.
• W1799025303 creator A5007501845 @default.
• W1799025303 date "1989-11-01" @default.
• W1799025303 modified "2023-10-16" @default.
• W1799025303 title "Regulation of type I (epidermal) transglutaminase mRNA levels during squamous differentiation: down regulation by retinoids." @default.
• W1799025303 cites W1243723833 @default.
• W1799025303 cites W1509951428 @default.
• W1799025303 cites W1539901397 @default.
• W1799025303 cites W1560714476 @default.
• W1799025303 cites W1591434433 @default.
• W1799025303 cites W1612390895 @default.
• W1799025303 cites W1775166666 @default.
• W1799025303 cites W1913952795 @default.
• W1799025303 cites W1971550375 @default.
• W1799025303 cites W1974469880 @default.
• W1799025303 cites W1981443985 @default.
• W1799025303 cites W1987708536 @default.
• W1799025303 cites W1989468162 @default.
• W1799025303 cites W1995420892 @default.
• W1799025303 cites W1997226580 @default.
• W1799025303 cites W1997287630 @default.
• W1799025303 cites W1999444368 @default.
• W1799025303 cites W2001323678 @default.
• W1799025303 cites W2009310436 @default.
• W1799025303 cites W2013405071 @default.
• W1799025303 cites W2015339616 @default.
• W1799025303 cites W2019485800 @default.
• W1799025303 cites W2020782906 @default.
• W1799025303 cites W2022608661 @default.
• W1799025303 cites W2049791242 @default.
• W1799025303 cites W2061178138 @default.
• W1799025303 cites W2064251625 @default.
• W1799025303 cites W2072233737 @default.
• W1799025303 cites W2085137882 @default.
• W1799025303 cites W2138270253 @default.
• W1799025303 cites W2144634347 @default.
• W1799025303 cites W2161229567 @default.
• W1799025303 cites W2329225250 @default.
• W1799025303 cites W2404216745 @default.
• W1799025303 cites W2442676031 @default.
• W1799025303 doi "https://doi.org/10.1128/mcb.9.11.4846" @default.
• W1799025303 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/363634" @default.
• W1799025303 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2574824" @default.
• W1799025303 hasPublicationYear "1989" @default.
• W1799025303 type Work @default.
• W1799025303 sameAs 1799025303 @default.
• W1799025303 citedByCount "101" @default.
• W1799025303 countsByYear W17990253032018 @default.
• W1799025303 crossrefType "journal-article" @default.
• W1799025303 hasAuthorship W1799025303A5006295693 @default.
• W1799025303 hasAuthorship W1799025303A5007501845 @default.
• W1799025303 hasBestOaLocation W17990253031 @default.
• W1799025303 hasConcept C104317684 @default.
• W1799025303 hasConcept C105580179 @default.
• W1799025303 hasConcept C148738053 @default.
• W1799025303 hasConcept C150194340 @default.
• W1799025303 hasConcept C153911025 @default.
• W1799025303 hasConcept C178498320 @default.
• W1799025303 hasConcept C181199279 @default.
• W1799025303 hasConcept C187882448 @default.
• W1799025303 hasConcept C2779963572 @default.
• W1799025303 hasConcept C2781121885 @default.
• W1799025303 hasConcept C54355233 @default.
• W1799025303 hasConcept C55493867 @default.
• W1799025303 hasConcept C67705224 @default.
• W1799025303 hasConcept C81885089 @default.
• W1799025303 hasConcept C86803240 @default.
• W1799025303 hasConceptScore W1799025303C104317684 @default.
• W1799025303 hasConceptScore W1799025303C105580179 @default.
• W1799025303 hasConceptScore W1799025303C148738053 @default.
• W1799025303 hasConceptScore W1799025303C150194340 @default.
• W1799025303 hasConceptScore W1799025303C153911025 @default.
• W1799025303 hasConceptScore W1799025303C178498320 @default.
• W1799025303 hasConceptScore W1799025303C181199279 @default.
• W1799025303 hasConceptScore W1799025303C187882448 @default.
• W1799025303 hasConceptScore W1799025303C2779963572 @default.
• W1799025303 hasConceptScore W1799025303C2781121885 @default.
• W1799025303 hasConceptScore W1799025303C54355233 @default.
• W1799025303 hasConceptScore W1799025303C55493867 @default.
• W1799025303 hasConceptScore W1799025303C67705224 @default.
• W1799025303 hasConceptScore W1799025303C81885089 @default.
• W1799025303 hasConceptScore W1799025303C86803240 @default.
• W1799025303 hasIssue "11" @default.
• W1799025303 hasLocation W17990253031 @default.
• W1799025303 hasLocation W17990253032 @default.
• W1799025303 hasLocation W17990253033 @default.
• W1799025303 hasOpenAccess W1799025303 @default.
• W1799025303 hasPrimaryLocation W17990253031 @default.
• W1799025303 hasRelatedWork W1799025303 @default.
• W1799025303 hasRelatedWork W2012388266 @default.
• W1799025303 hasRelatedWork W2024081264 @default.
• W1799025303 hasRelatedWork W2076716879 @default.
• W1799025303 hasRelatedWork W2077058303 @default.
• W1799025303 hasRelatedWork W2403704047 @default.
• W1799025303 hasRelatedWork W3140818227 @default.
• W1799025303 hasRelatedWork W4240392768 @default.

• next